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  • Title: Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3-ones for evaluation of antimicrobial and anticancer activity.
    Author: Sanna P, Carta A, Loriga M, Zanetti S, Sechi L.
    Journal: Farmaco; 1998 Jul 30; 53(7):455-61. PubMed ID: 9836457.
    Abstract:
    A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.
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