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  • Title: Pyogenic granuloma-like lesions in a patient using topical tretinoin.
    Author: MacKenzie-Wood AR, Wood G.
    Journal: Australas J Dermatol; 1998 Nov; 39(4):248-50. PubMed ID: 9838723.
    Abstract:
    A 16-year-old male developed numerous pyogenic granuloma like-lesions across his neck, chest and back after 6 weeks isotretinoin therapy for cystic acne. The isotretinoin was ceased and he was commenced on oral steroids. After 6 weeks, the lesions were almost completely healed. However, due to worsening comedonal acne, the patient was commenced on topical tretinoin cream 0.05% twice daily to his chest. He was reviewed 2 weeks later and, surprisingly, 2 new pyogenic granuloma-like lesions had developed on his chest. These lesions persisted until the topical tretinoin was ceased 3 months later.
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