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  • Title: Teratoma with trisomy 16 in a baboon (Papio hamadryas).
    Author: Moore CM, McKeand J, Witte SM, Hubbard GB, Rogers J, Leland MM.
    Journal: Am J Primatol; 1998; 46(4):323-32. PubMed ID: 9839905.
    Abstract:
    A teratoma was found during a planned cesarean section in a 10-year-old primigravida baboon. This teratoma had a female sex chromosome complement and trisomy for chromosome 16. This is the first report of a teratoma in a baboon and the first report of a chromosomal abnormality in a nonhuman primate teratoma. It is also the first case in a nonhuman primate to address the mechanism of origin. Through the use of genetic markers from human chromosomes 5, 8 and 17, the origin of the teratoma was shown to be most consistent with failure of meiosis II or endoreduplication in a mature ovum, while the trisomy for chromosome 16 originated after the formation of the tumor.
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