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  • Title: Long-term effect of prophylactic endoscopic injection sclerotherapy on liver function.
    Author: Murata K, Sugimoto K, Okuda K, Shimizu A, Takase K, Nakano T, Tameda Y.
    Journal: Hepatogastroenterology; 1998; 45(23):1726-30. PubMed ID: 9840136.
    Abstract:
    BACKGROUND/AIMS: The aim of this study was to investigate the long term effect of prophylactic endoscopic injection sclerotherapy (EIS) on liver function. METHODOLOGY: This study was a retrospective investigation of seventy-eight patients with liver cirrhosis, whose liver function was classified as Child's A before follow-up. Laboratory data were retrospectively examined before and after follow-up, and a comparison was made between the EIS group (n=21) and the non-treated group (n=57). RESULTS: In the 3 or more years of follow-up, cholinesterase and total cholesterol levels deteriorated in several severe-variceal cases. However, these levels did not deteriorate over the 3 or more years of follow-up in the EIS group. CONCLUSION: Prophylactic endoscopic injection sclerotherapy among patients with early stage LC may prevent the deterioration of liver function.
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