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  • Title: Progress toward eliminating Haemophilus influenzae type b disease among infants and children--United States, 1987-1997.
    Author: Centers for Disease Control and Prevention (CDC).
    Journal: MMWR Morb Mortal Wkly Rep; 1998 Nov 27; 47(46):993-8. PubMed ID: 9843325.
    Abstract:
    Haemophilus influenzae type b (Hib) causes serious invasive diseases among previously healthy children aged <5 years. Before the availability of conjugate vaccines in 1988, Hib was the most common cause of bacterial meningitis among preschool-aged children. Since 1993, the incidence of Hib invasive disease (defined as illness clinically compatible with invasive disease such as meningitis or sepsis, with isolation of the bacterium from a normally sterile site) among children aged <5 years has declined >95% in the United States. This report describes the continued decline of reported Hib invasive disease cases and underscores the need for investigation of Haemophilus influenzae (Hi) invasive disease cases.
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