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  • Title: [Analysis of in vivo and in vitro radioisotopic tests for studying hypothyroidism. Statistical study of parameters coming from routine investigations in normal subjects and hypothyroid patients].
    Author: Vallée G, Fandard J, Morin M, Nouchy J.
    Journal: Ann Biol Clin (Paris); 1976; 34(3):173-90. PubMed ID: 984524.
    Abstract:
    This report analyses quantitative data collected during spontaneous examination in normal subjects and in hypothyroid subjects, attempting to determine what figures obtained in this way can provide in the diagnosis of this disease. 125I tests in vitro today play a very important role and suffice der detection provided radio-immunoassay is carried out, whether the latter concerns iodine hormones or the thyreotropic pituitary hormone and provided the diagnosis is not confirmed by one single examination. The 131I kinetic test helps in classification of the hypothyroidism. Naturally, only further tests will permit us to determine certain causes (thyroid scan, Querido's test, TRF test, anionic competition, immunological study, etc.). Chemical estimations of stable iodine (127I) no longer have any place in this routine assessment, except that the total iodine is essential to interpret the kinetics in vivo.
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