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  • Title: Mucosal morphologic alterations in Thiry-Vella fistulas.
    Author: Halliwell WH, Schmidt DA, Hutcheson DP.
    Journal: Am J Vet Res; 1976 Nov; 37(11):1363-5. PubMed ID: 984570.
    Abstract:
    Three Thiry-Vella fistulas were surgically placed in each of 9 dogs to study the effects of x-irradiation on isolated loops of small intestine. Mucosal biopsy samples were removed from the fistulas for 5 days at 24-hour intervals after surgical operation to assess the morphologic alterations that occurred in the fistula mucosa following surgical isolation. There was a reduction of villus height during the 1st day, reduction of crypt depth on days 2 and 3, and stabilization of villus height and crypt depth during days 3 to 5 after surgical operation. The surgical technique and morphologic alterations observed in the mucosa of the fistulas during the 5 days after surgery are described.
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