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  • Title: Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G.
    Author: Vasi J, Svensson J, Frick IM, Müller HP.
    Journal: Infect Immun; 1999 Jan; 67(1):413-6. PubMed ID: 9864244.
    Abstract:
    Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the Fc and Fab parts.
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