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  • Title: [Analgesic agents: comparative evaluation, mechanisms of action, prospects].
    Author: Churiukanov VV.
    Journal: Anesteziol Reanimatol; 1998; (5):4-11. PubMed ID: 9866237.
    Abstract:
    A classification of analgesics based on the localization and mechanisms of their action is proposed. Opioid analgesics are compared: opioid receptor agonists, agonists-antagonists, and partial agonists. Central-action nonopioid analgesics are listed: alpha 2-adrenomimetics, Na- and K-channel blockers, reverse monoamine neuronal capture inhibitors, stimulating amino acid antagonists, etc. Peripheral-action analgesics (cycloxygenase inhibitors) are described.
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