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  • Title: [Usefulness of CT-guided aspiration biopsy in combination with rapid cytology for diagnosis of benign pulmonary lesions].
    Author: Kodama F, Ogawa T, Tanabe Y.
    Journal: Nihon Igaku Hoshasen Gakkai Zasshi; 1998 Nov; 58(13):745-50. PubMed ID: 9866991.
    Abstract:
    PURPOSE: To evaluate the diagnostic accuracy of computed tomography (CT)-guided aspiration biopsy in combination with rapid cytology for benign pulmonary lesions. MATERIALS AND METHODS: We performed percutaneous aspiration biopsy under CT guidance in combination with a rapid cytologic examination in 91 patients with pulmonary lesions. A 21-gauge modified Menghini needle coaxially placed through an 18-gauge needle was used in this procedure. Thirty-one lesions that were confirmed as a benign pulmonary lesion histologically, serologically, bacteriologically and/or clinically were evaluated in this study. RESULTS: In 28(90.3%) of 31 lesions, sufficient material for cytologic diagnosis was obtained from the aspiration biopsy. Specific benign diagnosis for benign disease was obtained in 13 lesions (41.9%), while nonspecific diagnosis for benign disease was obtained in 15 lesions (48.4%). The overall accuracy of the rapid cytological examination was 90.3%. Pneumothorax developed in 17 patients (54.8%), with 7 patients (22.6%) requiring chest tube drainage. Only one patient complained of mild hemoptysis, which subsided with hemostatic agents. CONCLUSION: Percutaneous aspiration biopsy combined with a rapid cytologic diagnosis provides a high degree of accuracy in the diagnosis of benign pulmonary lesions.
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