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  • Title: Development of primary leiomyosarcoma of the sternum postirradiation: report of a case.
    Author: Aoki T, Ozeki Y, Watanabe M, Tanaka S, Isaki H, Terahata S.
    Journal: Surg Today; 1998; 28(12):1326-8. PubMed ID: 9872562.
    Abstract:
    We report herein the case of a 30-year-old man who developed a primary leiomyosarcoma (LMS) 11 years after undergoing a median sternotomy for mediastinal seminoma followed by 50 Gy radiotherapy. He was given two courses of chemotherapy, resulting in 90% tumor regression, after which resection of the tumor with adjacent chest wall structures was carried out. Reconstruction was performed using a methylmethacrylate prosthesis prepared preoperatively. Postoperatively, he received two additional courses of chemotherapy and has had no sign of recurrence for 45 months.
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