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  • Title: Inhibition of electric eel acetylcholinesterase by porphin compounds.
    Author: Lee BH, Park MB, Yu BS.
    Journal: Bioorg Med Chem Lett; 1998 Jun 16; 8(12):1467-70. PubMed ID: 9873371.
    Abstract:
    Synthetic porphin compounds have been found to be reversible inhibitors of acetylcholinesterase from electric eel with Ki values of microM range. It seems that the number and position of fluorine on the phenyl ring and metal of an inhibitor play an important role for binding of an inhibitor to the enzyme active site.
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