These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Identification of the mebendazole polymorphic form present in raw materials and tablets available in South Africa.
    Author: Liebenberg W, Dekker TG, Lötter AP, de Villiers MM.
    Journal: Drug Dev Ind Pharm; 1998 May; 24(5):485-8. PubMed ID: 9876612.
    Abstract:
    A preformulation study of four different raw materials of mebendazole showed that three samples were polymorph C and the other polymorph A, or a mixture of form A and B. X-ray powder diffractometry and infrared spectroscopy indicated that this powder could be form B, but powder dissolution, for which a much slower dissolution was obtained, suggests polymorph A. Literature prescribes the use of polymorph C pharmaceutically, but generic manufacturers should be aware that forms other than C are still available on the market. The four mebendazole tablets currently available in South Africa were also tested and it was found that all of them contained polymorph C.
    [Abstract] [Full Text] [Related] [New Search]