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  • Title: A fibre-free alginate dressing in the treatment of split thickness skin graft donor sites.
    Author: Steenfos HH, Agren MS.
    Journal: J Eur Acad Dermatol Venereol; 1998 Nov; 11(3):252-6. PubMed ID: 9883438.
    Abstract:
    BACKGROUND: Alginate dressings are gaining acceptance in would management although comparative published data with conventional treatment is inconclusive. AIMS: The aim of this randomised controlled study was to compare a fibre-free alginate dressing (Comfeel SeaSorb) with conventional treatment of standardised split-thickness skin graft donor sites in 17 patients regarding initial absorption of blood and healing. RESULTS: The alginate dressing absorbed 40% (P < 0.05) more blood, measured as total iron content of used dressings, during the first 10 post-wounding minutes than fine mesh gauze, resulting in less subsequent bleeding. Light microscopic examination of punch biopsies obtained from 10 wounds on post-operative day 6 demonstrated that nine wounds treated with the alginate dressing compared with seven wounds treated conventionally with paraffin-impregnated gauze (Jelonet) were completely epithelialized, a statistically non-significant difference (P = 0.46). CONCLUSIONS: In conclusion, the fibre-free alginate dressing showed increased initial blood absorption resulting in quicker haemostasis but showed no greater beneficial effect on epithelialisation of split-thickness skin graft donor sites compared with conventional topical treatment.
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