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  • Title: [Optic glioma in children with type 1 neurofibromatosis].
    Author: Ben-Arush M, Goldberg H, Kuten A, Guilbord J, el-Hassid R.
    Journal: Harefuah; 1998 Oct; 135(7-8):264-7, 336. PubMed ID: 9885670.
    Abstract:
    During the period 1985-95 we treated 5 girls and 13 boys with optic glioma associated with Type 1 neurofibromatosis (median age 3 years, range 2-10 years). 6 were treated with radiotherapy alone, 1 with surgery and radiation therapy and 1 with chemotherapy in order to postpone irradiation to an older age; 1 is being followed with no therapy. All children are alive, 2-10 years from diagnosis (mean follow-up time 5.4 years). 3 had improvement of vision following therapy and in 4 visual ability stabilized, including the child being followed without treatment. In 1 vision deteriorated despite therapy.
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