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  • Title: Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula.
    Author: Márquez B, Verdier-Pinard P, Hamel E, Gerwick WH.
    Journal: Phytochemistry; 1998 Dec; 49(8):2387-9. PubMed ID: 9887531.
    Abstract:
    Curacin D is a novel brine shrimp toxic metabolite isolated from a Virgin Islands collection of the marine cyanobacterium Lyngbya majuscula. Structure elucidation of curacin D was accomplished through multidimensional NMR, GC/MS, and comparisons with curacin A. Curacin D provides new insights into structure-activity relationships in this natural product class as well as some aspects of the likely biosynthetic pathway of the curacins.
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