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  • Title: [Factors of post-transcription regulation of the rate of liver catalase synthesis in tumor-bearing rats].
    Author: Komov VP, Rakhmanina TF, Bulat AD.
    Journal: Biull Eksp Biol Med; 1976 Mar; 81(3):303-5. PubMed ID: 989027.
    Abstract:
    The factors-regulators of post-transcriptional regulation of the rate of catalase synthesis in the rat liver were studied under normal conditions and in carcinogenesis (the 2nd, 7th and the 14th days after the transplantation of Pliss lymphosarcoma). Factors Fact and Fing were purified from the supernatant and PH5-supernatant fractions of the rat liver by means of chromatography and rechromatography on DEAE-cellulose. A simple method of determination of the biological activity of these factors in vivo was proposed. Synthesis of catalase took place when (see article) (the 2nd and 14th days after the inosulation). The enzyme synthesis was absent when (see article) (7th day after the inoculation).
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