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  • Title: Skeletal and soft tissue sarcomas. Treatment with adjuvant immunotherapy.
    Author: Townsend CM, Eilber FR, Morton DL.
    Journal: JAMA; 1976 Nov 08; 236(19):2187-9. PubMed ID: 989809.
    Abstract:
    Because there is evidence for an active immunologic response against sarcoma, a clinical trial of adjuvant immunotherapy using bacillus Calmette-Guérin (BCG) and tumor cell vaccine was begun. Eleven of 18 patients with localized soft tissue sarcoma who received immunotherapy are free of disease, compared to only 5 of 15 treated by operation alone who are free of disease. Furthermore, immunotherapy also prolonged the median disease-free interval from 7.3 months to 15 months in the patients who experienced recurrence of their disease.
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