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  • Title: Glucosylquestiomycin, a novel antibiotic from Microbispora sp. TP-A0184: fermentation, isolation, structure determination, synthesis and biological activities.
    Author: Igarashi Y, Takagi K, Kajiura T, Furumai T, Oki T.
    Journal: J Antibiot (Tokyo); 1998 Oct; 51(10):915-20. PubMed ID: 9917004.
    Abstract:
    Glucosylquestiomycin, a novel N-glucopyranoside of questiomycin A, was isolated from the culture broth of Microbispora sp. TP-A0184. The absolute configuration of the sugar was determined as D-configuration by chemical synthesis. The new antibiotic showed antibacterial activity against gram-positive and -negative bacteria and yeasts and cytotoxic activity against U937 cells.
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