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  • Title: Thrombotic thrombocytopenic purpura: a rare but potential life-threatening complication following ticlopidine administration.
    Author: Jamar S, Vanderheyden M, Janssens L, Hermans L, Jamar R, Verstreken G.
    Journal: Acta Cardiol; 1998; 53(5):285-6. PubMed ID: 9922807.
    Abstract:
    Thrombotic thrombocytopenic purpura (TTP) is a known, although rare, complication of ticlopidine treatment. It typically appears within the first days or weeks after initiation of therapy. We describe a case of TTP in a 75-year-old patient, due to ticlopidine, occurring three weeks after coronary stent implantation. The patient responded favourably to fresh frozen plasma exchanges. We are reporting this case to emphasize that prognosis depends on prompt diagnosis and early treatment, implying careful biochemical monitoring.
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