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  • Title: HHV8 status in Kaposi's sarcoma associated with multiple myeloma.
    Author: Le Gars L, Agbalika F, Picard O, Kaplan G, Berenbaum F.
    Journal: Rev Rhum Engl Ed; 1998 Dec; 65(12):788-90. PubMed ID: 9923048.
    Abstract:
    Kaposi's sarcoma in its sporadic or HIV-related form is due to a gamma herpesvirus, the human herpes virus 8 (HHV8). No data have been published on the potential role of the HHV8 in Kaposi's sarcoma occurring in multiple myeloma patients. A case is reported of a patient in whom four serum samples taken between the diagnosis of multiple myeloma and the occurrence of a Kaposi's sarcoma one year later tested positive for antibody to the HHV8. Similar findings have been reported in patients with other types of Kaposi's sarcoma. PCR studies for HHV8 DNA were positive on a Kaposi's sarcoma biopsy but negative on a bone biopsy, militating against a role for the HHV8 in the genesis of multiple myeloma.
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