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  • Title: [The role of cytochrome c in preventing postresuscitation functional disorders of the central nervous system].
    Author: Boiarinov GA, Mukhina IV, Penknovich AA, Snopova LB, Iakovleva EI, Balandina MV, Zimin IuV, Prodanets NN.
    Journal: Eksp Klin Farmakol; 1998; 61(6):54-7. PubMed ID: 9929820.
    Abstract:
    The effect of intracarotid injection of cytochrome c on the course of the early postresuscitation period was studied in experimental animals (albino rats) after 5-min clinical death from acute blood loss. It was shown that the drug normalizes the disturbed metabolic processes in the brain, reduces the structural changes consequent upon total ischemia, stabilizes the activity of the cardiovascular system and, as a result of this, contributes to restoration of functional activity of the central nervous system in the early postresuscitation period.
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