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  • Title: [Verification and determination of opiates in the urine and blood with thin-layer chromatography followed by densitometry in fatal cases of drug abuse].
    Author: Valuch J, Bauer M.
    Journal: Soud Lek; 1998 Nov; 43(4):58-64. PubMed ID: 9931572.
    Abstract:
    Urine and blood concentrations of free and total morphin or 6-monoacetylmorphin were presented in fatal cases of morphin type opiates abuse. A solid phase extraction method was developed for isolation of drugs and their metabolities from biological material which used Separcol small columns with non-polar contents SI C 18T. Thin layer chromatography with densitometry anabled screening for quality evaluations. Resultes were compared with those obtained by fluoropolarizing immunodetection on Abbotts TDxFLx device. Possibility and cause of false positive results were discussed when using initial, screening, commercially available immunotests.
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