These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Acute myeloid leukemia with hypergranular cytoplasm accompanied by t(X;11)(q24;q23) and rearrangement of the MLL gene.
    Author: Nakata Y, Mori T, Yamazaki T, Suzuki T, Okazaki T, Kurosawa Y, Kinoshita A, Ohyashiki K, Nakazawa S.
    Journal: Leuk Res; 1999 Jan; 23(1):85-8. PubMed ID: 9933140.
    Abstract:
    This report describes a unique case of acute myeloid leukemia with hypergranular cytoplasm and t(X;11)(q24;q23). The breakpoint on 11q23 was identified within the MLL gene. The hypergranular cytoplasm of leukemic cells and the associated coagulopathy resembled a characteristic of acute promyelocytic leukemia, despite the absence of RARalpha gene rearrangement in this case. The Xq24 site possibly played a role in this atypical blast phenotype.
    [Abstract] [Full Text] [Related] [New Search]