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  • Title: Mercaptoacetyltriglycine diuretic renography and output efficiency measurement in renal transplant patients.
    Author: Spicer ST, Chi KK, Nankivell BJ, Larcos G, Farlow DC, Choong KK, Chapman JR, Gruenewald SM.
    Journal: Eur J Nucl Med; 1999 Feb; 26(2):152-4. PubMed ID: 9933349.
    Abstract:
    Suspected urinary tract obstruction following renal transplantation presents a diagnostic dilemma. The purposes of this study were: (1) to establish a normal range of measurement of output efficiency (OE) in the renal transplant population, and (2) to assess prospectively the usefulness of OE in the setting of allograft obstruction. Twenty-two renal transplant patients with stable renal function and no evidence of hydronephrosis on serial ultrasound examination had a diuretic mercaptoacetyltriglycine scan with calculation of OE. Three renal transplant patients with confirmed graft obstruction were also studied. Standard qualitative and quantitative parameters as well as OE were calculated. The mean OE for the 22 normal renal transplant patients was 86.3%+/-3.7% (range: 77%-91%). OE values in the three obstructed patients were 59%, 68% and 75% respectively. It is concluded that OE should normally exceed 77% in renal graft recipients. OE is a promising means of diagnosing functional obstruction in these patients.
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