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  • Title: Cancer and adenomatous polyp distribution in the colorectum.
    Author: Ikeda Y, Mori M, Yoshizumi T, Sugimachi K.
    Journal: Am J Gastroenterol; 1999 Jan; 94(1):191-3. PubMed ID: 9934754.
    Abstract:
    OBJECTIVE: To examine the possible role of adenomatous polyps in colorectal cancer development, this study focused on the relationship of the distribution between adenomatous polyps and cancer in the colorectum. METHODS: The distribution of 753 adenomatous polyps was compared with that of 35 colorectal cancer lesions in 510 male patients ranging from 45 to 55 yr of age who underwent a total colonoscopy. RESULTS: The incidence of cancer significantly increased with a distal shift in the colorectal sites in comparison with that of adenomatous polyps (p < 0.02). CONCLUSION: The different distribution between adenomatous polyps and cancer thus suggested that adenomatous polyps at various colorectal sites appear to have a different malignant potential for cancer development.
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