These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Evidence for splicing of interrupted immunoglobulin variable and constant region sequences in nuclear RNA.
    Author: Rabbitts TH.
    Journal: Nature; 1978 Sep 28; 275(5678):291-6. PubMed ID: 99668.
    Abstract:
    Evidence is presented that the mouse light-chain coding sequence is interrupted in a 27S nuclear RNA species, whereas the sequence is continuous in both a 13S nuclear RNA and in cytoplasmic mRNA. The discontinuity of coding regions in the 27S nuclear RNA parallels the situation found in myeloma DNA and indicates, therefore, that the removal of interruptions in the V and C regions occurs at the level of nuclear RNA.
    [Abstract] [Full Text] [Related] [New Search]