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  • Title: The effects of ligation of vas deferens, corpus epididymidis and vasa efferentia on the testicular function in rats.
    Author: Kuwahara M.
    Journal: Tohoku J Exp Med; 1976 Nov; 120(3):251-7. PubMed ID: 996849.
    Abstract:
    The effects of ligation of the vas deferens, the corpus epididymidis and the vasa efferentia on the testicular function were studied in sexually mature rats. The significant decrease in the testicular weight was observed after ligation of the corpus epididymidis and the vasa efferentia. However, neither the weight of the ventral prostate and of the seminal vesicle, nor the plasma testosterone level showed significant changes. The results suggest that the ligation at the three locations would not affect the endocrine function of the testis. The changes in the testis would mainly affect the spermatogenesis. The effects of sperm stasis on the testicular function were also discussed. Testicular function in sexually mature rats was studied following ligation of the vas deferens, corpus epididymis, and vasa efferentia. Ligation of the corpus epididymis and vasa efferentia significantly (p less than .01) reduced testicular weight, but did not markedly affect the weights of the ventral prostate and seminal vesicle, nor did it markedly alter plasma testosterone levels. The weight of the epididymis head was significantly (p less than .01) increased in the corpus epididymis ligated group, as was the weight of the epididymal tail in vasoligated animals. The data suggest that ligation at the 3 sites does not affect the endocrine function of the testis. The influence of sperm stasis on testicular function is discussed.
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