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  • Title: Nutritional effects of a D-methionine-containing solution on AH109A hepatoma-bearing rats.
    Author: Sasamura T, Matsuda A, Kokuba Y.
    Journal: Biosci Biotechnol Biochem; 1998 Dec; 62(12):2418-20. PubMed ID: 9972268.
    Abstract:
    The effects of a D-methionine-containing solution (DMCS) on the nutritional status of AH109A hepatomabearing rats receiving total parenteral nutrition were studied. The DMCS solution inhibited the decrease of transferrin in the plasma of tumor-bearing rats when compared with the effect of an L-methionine-containing solution. The survival time was also significantly prolonged in the DMCS-treated rats. These results indicate that DMCS had a beneficial effect on the malnutrition induced in tumor-bearing rats and would be a useful amino acid solution for the nutritional support of cancer patients.
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