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Title: Effect of methotrexate on tubal epithelium. A report of three cases. Author: Lécuru F, Robin F, Taurelle R, Bernard JP, Vildé F. Journal: J Reprod Med; 1999 Jan; 44(1):46-8. PubMed ID: 9987739. Abstract: BACKGROUND: Tubal effects of methotrexate injections have been poorly reported. CASES: Three fallopian tubes were examined with light microscopy 9-13 months after tubal methotrexate injection (one case) and intramuscular methotrexate injection (two cases) given for the treatment of unruptured ectopic pregnancies. No evidence of tubal damage was found. CONCLUSION: These three cases confirm previous experimental and clinical data showing the absence of a direct adverse effect of methotrexate on the fallopian tubes in the treatment of ectopic pregnancy.[Abstract] [Full Text] [Related] [New Search]