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Title: Chemical and enzymatic synthesis of glycoconjugates. 5: One-pot regioselective synthesis of bioactive galactobiosides using a CLONEZYME thermophilic glycosidase library. Author: Li J, Robertson DE, Short JM, Wang PG. Journal: Bioorg Med Chem Lett; 1999 Jan 04; 9(1):35-8. PubMed ID: 9990452. Abstract: Enzymatic synthesis of galactobiosides using a versatile CLONEZYME thermostable glycosidase library was studied. One-pot transglycosylation reactions were demonstrated to synthesize beta(1-->4), beta(1-->6), and alpha(1-->6) disaccharide sequences with high regioselectivity and moderate to high yields.[Abstract] [Full Text] [Related] [New Search]