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  • Title: In vitro transformation of rodent cells by simian adenovirus 7 and bovine adenovirus type 3 (strain WBR-1).
    Author: Panigrahy B, McCormick KJ, Trentin JJ.
    Journal: Am J Vet Res; 1976 Dec; 37(12):1503-4. PubMed ID: 999075.
    Abstract:
    Hamster, rat, and mouse embryo cells were quantitatively transformed by simian adenovirus 7 with maximum efficiencies of 2.1 X 10(5), and 2.5 X 10(5) plaque-forming unit/focus-forming unit, respectively. Bovine adenovirus type 3 did not transform rat or mouse embryo cells, but transformed hamster embryo cells with a maximum efficiency of 3.4 X 10(4) plaque-forming unit/focus-forming unit. All of the transformed cells were tumorigenic in appropriate hosts and possessed viral-specific T-antigen.
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