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  • Title: Growth hormone response in fetal alcohol syndrome.
    Author: Tze WJ, Friesen HG, MacLeod PM.
    Journal: Arch Dis Child; 1976 Sep; 51(9):703-6. PubMed ID: 999327.
    Abstract:
    In the fetal alcohol syndrome (FAS) there is severe physical growth retardation both prenatally and postnatally. Secretion of growth hormone (GH) after insulin-induced hypoglycaemia and arginine infusion was analysed in 5 cases of FAS to find out whether changes in GH secretion might account for the abnormal growth pattern. Results showed a normal or slight hyper-response of GH up to 150 ng/ml, and normal somatomedin activity in those blood samples with high GH level. It was concluded that the growth retardation in FAS is not caused by GH or somatomedin deficiencies.
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