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166 related items for PubMed ID: 10037473
1. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. Guo Q, Sebastian L, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP. J Neurochem; 1999 Mar; 72(3):1019-29. PubMed ID: 10037473 [Abstract] [Full Text] [Related]
5. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J. J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846 [Abstract] [Full Text] [Related]
6. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. Siman R, Reaume AG, Savage MJ, Trusko S, Lin YG, Scott RW, Flood DG. J Neurosci; 2000 Dec 01; 20(23):8717-26. PubMed ID: 11102478 [Abstract] [Full Text] [Related]
7. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease. Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA. J Neurochem; 2006 Mar 01; 96(5):1322-35. PubMed ID: 16478525 [Abstract] [Full Text] [Related]
8. Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice. Xie J, Chang X, Zhang X, Guo Q. Brain Res; 2001 Oct 05; 915(1):1-10. PubMed ID: 11578614 [Abstract] [Full Text] [Related]
9. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP. Nat Med; 1999 Jan 05; 5(1):101-6. PubMed ID: 9883847 [Abstract] [Full Text] [Related]
10. Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis. Mattson MP, Zhu H, Yu J, Kindy MS. J Neurosci; 2000 Feb 15; 20(4):1358-64. PubMed ID: 10662826 [Abstract] [Full Text] [Related]
11. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP. J Neurosci; 1997 Jun 01; 17(11):4212-22. PubMed ID: 9151738 [Abstract] [Full Text] [Related]
12. Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice. Eckert A, Schindowski K, Leutner S, Luckhaus C, Touchet N, Czech C, Müller WE. Neurobiol Dis; 2001 Apr 01; 8(2):331-42. PubMed ID: 11300728 [Abstract] [Full Text] [Related]
13. Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation. Zhu H, Guo Q, Mattson MP. Brain Res; 1999 Sep 18; 842(1):224-9. PubMed ID: 10526115 [Abstract] [Full Text] [Related]
14. Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production. Keller JN, Guo Q, Holtsberg FW, Bruce-Keller AJ, Mattson MP. J Neurosci; 1998 Jun 15; 18(12):4439-50. PubMed ID: 9614221 [Abstract] [Full Text] [Related]
15. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. Chan SL, Mayne M, Holden CP, Geiger JD, Mattson MP. J Biol Chem; 2000 Jun 16; 275(24):18195-200. PubMed ID: 10764737 [Abstract] [Full Text] [Related]
16. Caspase-2 mediates neuronal cell death induced by beta-amyloid. Troy CM, Rabacchi SA, Friedman WJ, Frappier TF, Brown K, Shelanski ML. J Neurosci; 2000 Feb 15; 20(4):1386-92. PubMed ID: 10662829 [Abstract] [Full Text] [Related]
17. Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain. Lee J, Chan SL, Mattson MP. Neuromolecular Med; 2002 Feb 15; 2(1):29-45. PubMed ID: 12230303 [Abstract] [Full Text] [Related]
18. Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation. Pigino G, Pelsman A, Mori H, Busciglio J. J Neurosci; 2001 Feb 01; 21(3):834-42. PubMed ID: 11157069 [Abstract] [Full Text] [Related]
19. Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons. Yang B, Sun X, Lashuel H, Zhang Y. Neurosci Bull; 2012 Jun 01; 28(3):233-9. PubMed ID: 22622822 [Abstract] [Full Text] [Related]
20. Enhancement of activation of caspases by presenilin 1 gene mutations and its inhibition by secretase inhibitors. Miyoshi K, Ohyagi Y, Sakae N, Motomura K, Ma L, Taniwaki T, Furuya H, Tabira T, Kira J. J Alzheimers Dis; 2009 Jun 01; 16(3):551-64. PubMed ID: 19276550 [Abstract] [Full Text] [Related] Page: [Next] [New Search]