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Journal Abstract Search

602 related items for PubMed ID: 10072683

  • 1. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
    Shi J, McAtee JJ, Schlueter Wirtz S, Tharnish P, Juodawlkis A, Liotta DC, Schinazi RF.
    J Med Chem; 1999 Mar 11; 42(5):859-67. PubMed ID: 10072683
    [Abstract] [Full Text] [Related]

  • 2. A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides.
    Siddiqui MA, Hughes SH, Boyer PL, Mitsuya H, Van QN, George C, Sarafinanos SG, Marquez VE.
    J Med Chem; 2004 Oct 07; 47(21):5041-8. PubMed ID: 15456247
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  • 3. N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.
    Shi J, Mathew JS, Tharnish PM, Rachakonda S, Pai SB, Adams M, Grier JP, Gallagher K, Zhang H, Wu JT, Shi G, Geleziunas R, Erickson-Viitanen S, Stuyver L, Otto MJ, Watanabe KA, Schinazi RF.
    Antivir Chem Chemother; 2003 Mar 07; 14(2):81-90. PubMed ID: 12856919
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  • 4. Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP.
    Murakami E, Ray AS, Schinazi RF, Anderson KS.
    Antiviral Res; 2004 Apr 07; 62(1):57-64. PubMed ID: 15026203
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  • 5. l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.
    Chong Y, Gumina G, Mathew JS, Schinazi RF, Chu CK.
    J Med Chem; 2003 Jul 17; 46(15):3245-56. PubMed ID: 12852755
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  • 7. Interaction of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluoro-CTP with human immunodeficiency virus-1 reverse transcriptase and human DNA polymerases: implications for human immunodeficiency virus drug design.
    Kukhanova M, Li X, Chen SH, King I, Doyle T, Prusoff W, Cheng YC.
    Mol Pharmacol; 1998 May 17; 53(5):801-7. PubMed ID: 9584205
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  • 8. Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
    Wang J, Jin Y, Rapp KL, Bennett M, Schinazi RF, Chu CK.
    J Med Chem; 2005 Jun 02; 48(11):3736-48. PubMed ID: 15916425
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  • 9. Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases γ and β by thiated 3'-fluorothymidine analogue 5'-triphosphates.
    Wińska P, Miazga A, Poznański J, Kulikowski T.
    Antiviral Res; 2010 Nov 02; 88(2):176-81. PubMed ID: 20739003
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase.
    Wang G, Boyle N, Chen F, Rajappan V, Fagan P, Brooks JL, Hurd T, Leeds JM, Rajwanshi VK, Jin Y, Prhavc M, Bruice TW, Cook PD.
    J Med Chem; 2004 Dec 30; 47(27):6902-13. PubMed ID: 15615539
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  • 11. Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors.
    Xu B, Sun Y, Guo Y, Cao Y, Yu T.
    Bioorg Med Chem; 2009 Apr 01; 17(7):2767-74. PubMed ID: 19269831
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  • 12. In vitro selection and analysis of human immunodeficiency virus type 1 resistant to derivatives of beta-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine.
    Hammond JL, Parikh UM, Koontz DL, Schlueter-Wirtz S, Chu CK, Bazmi HZ, Schinazi RF, Mellors JW.
    Antimicrob Agents Chemother; 2005 Sep 01; 49(9):3930-2. PubMed ID: 16127074
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  • 13. Synthesis and biological evaluation of 2',3'-dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).
    Lin TS, Luo MZ, Liu MC, Pai SB, Dutschman GE, Cheng YC.
    J Med Chem; 1994 Mar 18; 37(6):798-803. PubMed ID: 8145230
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  • 14. HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
    Geleziunas R, Gallagher K, Zhang H, Bacheler L, Garber S, Wu JT, Shi G, Otto MJ, Schinazi RF, Erickson-Viitanen S.
    Antivir Chem Chemother; 2003 Jan 18; 14(1):49-59. PubMed ID: 12790516
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  • 15. Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues.
    Wang Y, Chen FE, Balzarini J, De Clercq E, Pannecouque C.
    Chem Biodivers; 2008 Jan 18; 5(1):168-76. PubMed ID: 18205120
    [Abstract] [Full Text] [Related]

  • 16. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
    Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G.
    J Med Chem; 2005 Nov 17; 48(23):7153-65. PubMed ID: 16279773
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  • 20. The design and synthesis of N-1-alkylated-5-aminoarylalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors.
    Lu X, Chen Y, Guo Y, Liu Z, Shi Y, Xu Y, Wang X, Zhang Z, Liu J.
    Bioorg Med Chem; 2007 Dec 01; 15(23):7399-407. PubMed ID: 17870545
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