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Journal Abstract Search

103 related items for PubMed ID: 10079878

  • 1. Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5'-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents.
    Jan ST, Shih MJ, Venkatachalam TK, D'Cruz OJ, Chen CL, Uckun FM.
    Antivir Chem Chemother; 1999 Jan; 10(1):39-46. PubMed ID: 10079878
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  • 2. Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
    D'Cruz OJ, Shih MJ, Yiv SH, Chen CL, Uckun FM.
    Mol Hum Reprod; 1999 May; 5(5):421-32. PubMed ID: 10338365
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  • 3. Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus.
    D'Cruz OJ, Venkatachalam TK, Zhu Z, Shih MJ, Uckun FM.
    Biol Reprod; 1998 Sep; 59(3):503-15. PubMed ID: 9716547
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  • 5. AZT-5'-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent.
    Jan ST, Zhu Z, Tai HL, Shih MJ, Venkatachalam TK, Uckun FM.
    Antivir Chem Chemother; 1999 Jan; 10(1):47-52. PubMed ID: 10079879
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  • 8. In vivo biodistribution, pharmacokinetic parameters, and brain uptake of 5-halo-y-methoxy(or ethoxy)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs of 3'-azido-3'-deoxythymidine.
    Wang L, Morin KW, Kumar R, Cheraghali M, Todd KG, Baker GB, Knaus EE, Wiebe LI.
    J Med Chem; 1996 Feb 16; 39(4):826-33. PubMed ID: 8632406
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  • 9. Potent dual anti-HIV and spermicidal activities of novel oxovanadium(V) complexes with thiourea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    D'Cruz OJ, Dong Y, Uckun FM.
    Biochem Biophys Res Commun; 2003 Mar 07; 302(2):253-64. PubMed ID: 12604339
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  • 13. Lack of adverse effects on fertility of female CD-1 mice exposed to repetitive intravaginal gel-microemulsion formulation of a dual-function anti-HIV agent: aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07).
    D'Cruz OJ, Uckun FM.
    J Appl Toxicol; 2001 Mar 07; 21(4):317-22. PubMed ID: 11481666
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  • 14. Synthesis and antiviral (HIV-1, HBV) activities of 5-halo-6-methoxy(or azido)-5,6-dihydro-3'-fluoro-3'-deoxythymidine diastereomers. Potential prodrugs to 3'-fluoro-3'-deoxythymidine.
    Kumar R, Wang L, Wiebe LI, Knaus EE.
    J Med Chem; 1994 Oct 14; 37(21):3554-60. PubMed ID: 7932583
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  • 15. Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in B(6)C(3)F(1) mice.
    D'Cruz OJ, Waurzyniak B, Yiv SH, Uckun FM.
    Contraception; 2000 Jan 14; 61(1):69-76. PubMed ID: 10745072
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  • 18. Short-Term (13-week) toxicity study of 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent, in B6C3F1 mice.
    D'Cruz OJ, Uckun FM.
    Toxicol Sci; 2001 Apr 14; 60(2):373-8. PubMed ID: 11248150
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