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Journal Abstract Search


127 related items for PubMed ID: 10082277

  • 21. Modulation of the clozapine structure increases its selectivity for the dopamine D4 receptor.
    Liégeois JF, Bruhwyler J, Damas J, Rogister F, Masereel B, Geczy J, Delarge J.
    Eur J Pharmacol; 1995 Feb 06; 273(3):R1-3. PubMed ID: 7737323
    [Abstract] [Full Text] [Related]

  • 22. The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists.
    Pugsley TA, Shih YH, Whetzel SZ, Zoski K, Van Leeuwen D, Akunne H, Mackenzie R, Heffner TG, Wustrow D, Wise LD.
    Prog Neuropsychopharmacol Biol Psychiatry; 2002 Feb 06; 26(2):219-26. PubMed ID: 11817497
    [Abstract] [Full Text] [Related]

  • 23. Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor.
    Patel S, Freedman S, Chapman KL, Emms F, Fletcher AE, Knowles M, Marwood R, Mcallister G, Myers J, Curtis N, Kulagowski JJ, Leeson PD, Ridgill M, Graham M, Matheson S, Rathbone D, Watt AP, Bristow LJ, Rupniak NM, Baskin E, Lynch JJ, Ragan CI.
    J Pharmacol Exp Ther; 1997 Nov 06; 283(2):636-47. PubMed ID: 9353380
    [Abstract] [Full Text] [Related]

  • 24. Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity.
    Cummings DF, Ericksen SS, Schetz JA.
    J Neurochem; 2009 Jul 06; 110(1):45-57. PubMed ID: 19486266
    [Abstract] [Full Text] [Related]

  • 25. The naphtosultam derivative RP 62203 (fananserin) has high affinity for the dopamine D4 receptor.
    Heuillet E, Petitet F, Mignani S, Malleron JL, Lavayre J, Néliat G, Doble A, Blanchard JC.
    Eur J Pharmacol; 1996 Oct 24; 314(1-2):229-33. PubMed ID: 8957240
    [Abstract] [Full Text] [Related]

  • 26. Syntheses and pharmacological evaluation of two potent antagonists for dopamine D4 receptors: [11C]YM-50001 and N-[2-[4-(4-Chlorophenyl)-piperizin-1-yl]ethyl]-3-[11C]methoxybenzamide.
    Zhang MR, Haradahira T, Maeda J, Okauchi T, Kawabe K, Noguchi J, Kida T, Suzuki K, Suhara T.
    Nucl Med Biol; 2002 Feb 24; 29(2):233-41. PubMed ID: 11823129
    [Abstract] [Full Text] [Related]

  • 27. Cloning, expression and characterization of a human dopamine D4.2 receptor (CHO K1 cells) and various D4.2/D2L chimeras (COS-7 cells).
    Shih YH, Chung FZ, Pugsley TA.
    Prog Neuropsychopharmacol Biol Psychiatry; 1997 Jan 24; 21(1):153-67. PubMed ID: 9075264
    [Abstract] [Full Text] [Related]

  • 28. Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors.
    Mierau J, Schneider FJ, Ensinger HA, Chio CL, Lajiness ME, Huff RM.
    Eur J Pharmacol; 1995 Jun 23; 290(1):29-36. PubMed ID: 7664822
    [Abstract] [Full Text] [Related]

  • 29. Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907.
    Pugsley TA, Davis MD, Akunne HC, MacKenzie RG, Shih YH, Damsma G, Wikstrom H, Whetzel SZ, Georgic LM, Cooke LW.
    J Pharmacol Exp Ther; 1995 Dec 23; 275(3):1355-66. PubMed ID: 8531103
    [Abstract] [Full Text] [Related]

  • 30. [3H]S33084: a novel, selective and potent radioligand at cloned, human dopamine D3 receptors.
    Cussac D, Newman-Tancredi A, Sezgin L, Millan MJ.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 May 23; 361(5):569-72. PubMed ID: 10832613
    [Abstract] [Full Text] [Related]

  • 31. Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic.
    Tadori Y, Miwa T, Tottori K, Burris KD, Stark A, Mori T, Kikuchi T.
    Eur J Pharmacol; 2005 May 16; 515(1-3):10-9. PubMed ID: 15894311
    [Abstract] [Full Text] [Related]

  • 32. Differential effects of [3H]nemonapride and [3H]spiperone binding on human dopamine D4 receptors.
    Hidaka K, Matsumoto M, Tada S, Tasaki Y, Yamaguchi T.
    Neurosci Lett; 1995 Feb 17; 186(2-3):145-8. PubMed ID: 7777184
    [Abstract] [Full Text] [Related]

  • 33. I. NGD 94-1: identification of a novel, high-affinity antagonist at the human dopamine D4 receptor.
    Tallman JF, Primus RJ, Brodbeck R, Cornfield L, Meade R, Woodruff K, Ross P, Thurkauf A, Gallager DW.
    J Pharmacol Exp Ther; 1997 Aug 17; 282(2):1011-9. PubMed ID: 9262370
    [Abstract] [Full Text] [Related]

  • 34. Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand.
    Seeman P, Van Tol HH.
    Eur J Pharmacol; 1995 Oct 15; 291(2):59-66. PubMed ID: 8566176
    [Abstract] [Full Text] [Related]

  • 35. Identification of a new selective dopamine D4 receptor ligand.
    Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY.
    Bioorg Med Chem; 2014 Jun 15; 22(12):3105-14. PubMed ID: 24800940
    [Abstract] [Full Text] [Related]

  • 36. Noradrenaline and adrenaline are high affinity agonists at dopamine D4 receptors.
    Newman-Tancredi A, Audinot-Bouchez V, Gobert A, Millan MJ.
    Eur J Pharmacol; 1997 Jan 29; 319(2-3):379-83. PubMed ID: 9042615
    [Abstract] [Full Text] [Related]

  • 37. 1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: a selective high-affinity antagonist for the human dopamine D(4) receptor with excellent selectivity over ion channels.
    Carling RW, Moore KW, Moyes CR, Jones EA, Bonner K, Emms F, Marwood R, Patel S, Patel S, Fletcher AE, Beer M, Sohal B, Pike A, Leeson PD.
    J Med Chem; 1999 Jul 15; 42(14):2706-15. PubMed ID: 10411491
    [Abstract] [Full Text] [Related]

  • 38. Rationally based efficacy tuning of selective dopamine d4 receptor ligands leading to the complete antagonist 2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213).
    Löber S, Hübner H, Utz W, Gmeiner P.
    J Med Chem; 2001 Aug 16; 44(17):2691-4. PubMed ID: 11495580
    [Abstract] [Full Text] [Related]

  • 39. Dopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals.
    Wilke RA, Hsu SF, Jackson MB.
    J Pharmacol Exp Ther; 1998 Feb 16; 284(2):542-8. PubMed ID: 9454795
    [Abstract] [Full Text] [Related]

  • 40. Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626.
    Bowery BJ, Razzaque Z, Emms F, Patel S, Freedman S, Bristow L, Kulagowski J, Seabrook GR.
    Br J Pharmacol; 1996 Dec 16; 119(7):1491-7. PubMed ID: 8968560
    [Abstract] [Full Text] [Related]


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