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Journal Abstract Search

991 related items for PubMed ID: 10086998

  • 1. Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds.
    Yumoto R, Murakami T, Nakamoto Y, Hasegawa R, Nagai J, Takano M.
    J Pharmacol Exp Ther; 1999 Apr; 289(1):149-55. PubMed ID: 10086998
    [Abstract] [Full Text] [Related]

  • 2. Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
    Yumoto R, Murakami T, Sanemasa M, Nasu R, Nagai J, Takano M.
    Drug Metab Dispos; 2001 Feb; 29(2):145-51. PubMed ID: 11159804
    [Abstract] [Full Text] [Related]

  • 3. P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.
    Wandel C, Kim RB, Kajiji S, Guengerich P, Wilkinson GR, Wood AJ.
    Cancer Res; 1999 Aug 15; 59(16):3944-8. PubMed ID: 10463589
    [Abstract] [Full Text] [Related]

  • 4. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
    Zhang Y, Guo X, Lin ET, Benet LZ.
    Drug Metab Dispos; 1998 Apr 15; 26(4):360-6. PubMed ID: 9531525
    [Abstract] [Full Text] [Related]

  • 5. Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro.
    Wandel C, Kim RB, Guengerich FP, Wood AJ.
    Drug Metab Dispos; 2000 Aug 15; 28(8):895-8. PubMed ID: 10901697
    [Abstract] [Full Text] [Related]

  • 6. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
    Dahan A, Amidon GL.
    Mol Pharm; 2009 Aug 15; 6(1):19-28. PubMed ID: 19248230
    [Abstract] [Full Text] [Related]

  • 7. In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model.
    Cummins CL, Salphati L, Reid MJ, Benet LZ.
    J Pharmacol Exp Ther; 2003 Apr 15; 305(1):306-14. PubMed ID: 12649383
    [Abstract] [Full Text] [Related]

  • 8. Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2.
    Collett A, Higgs NB, Sims E, Rowland M, Warhurst G.
    J Pharmacol Exp Ther; 1999 Jan 15; 288(1):171-8. PubMed ID: 9862768
    [Abstract] [Full Text] [Related]

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  • 10. Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells.
    Takano M, Hasegawa R, Fukuda T, Yumoto R, Nagai J, Murakami T.
    Eur J Pharmacol; 1998 Oct 09; 358(3):289-94. PubMed ID: 9822896
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory effect of Thai plant extracts on P-glycoprotein mediated efflux.
    Junyaprasert VB, Soonthornchareonnon N, Thongpraditchote S, Murakami T, Takano M.
    Phytother Res; 2006 Jan 09; 20(1):79-81. PubMed ID: 16397849
    [Abstract] [Full Text] [Related]

  • 12. Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    Yasuda K, Lan LB, Sanglard D, Furuya K, Schuetz JD, Schuetz EG.
    J Pharmacol Exp Ther; 2002 Oct 09; 303(1):323-32. PubMed ID: 12235267
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  • 14. Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.
    Shirasaka Y, Masaoka Y, Kataoka M, Sakuma S, Yamashita S.
    Drug Metab Dispos; 2008 May 09; 36(5):916-22. PubMed ID: 18276834
    [Abstract] [Full Text] [Related]

  • 15. Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor.
    Iqbal J, Hombach J, Matuszczak B, Bernkop-Schnürch A.
    J Control Release; 2010 Oct 01; 147(1):62-9. PubMed ID: 20603165
    [Abstract] [Full Text] [Related]

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  • 17. Nonlinear absorption of methylprednisolone by absorptive and secretory transporters.
    Tomita M, Watanabe A, Fujinaga I, Yamakawa T, Hayashi M.
    Int J Pharm; 2010 Mar 15; 387(1-2):1-6. PubMed ID: 19883743
    [Abstract] [Full Text] [Related]

  • 18. Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats.
    Machavaram KK, Gundu J, Yamsani MR.
    Pharmazie; 2004 Dec 15; 59(12):957-60. PubMed ID: 15638086
    [Abstract] [Full Text] [Related]

  • 19. P-glycoprotein-mediated efflux of indinavir metabolites in Caco-2 cells expressing cytochrome P450 3A4.
    Hochman JH, Chiba M, Yamazaki M, Tang C, Lin JH.
    J Pharmacol Exp Ther; 2001 Jul 15; 298(1):323-30. PubMed ID: 11408558
    [Abstract] [Full Text] [Related]

  • 20. Methadone inhibits rhodamine123 transport in Caco-2 cells.
    Störmer E, Perloff MD, von Moltke LL, Greenblatt DJ.
    Drug Metab Dispos; 2001 Jul 15; 29(7):954-6. PubMed ID: 11408360
    [Abstract] [Full Text] [Related]

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