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Journal Abstract Search

238 related items for PubMed ID: 10193901

  • 1. Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization.
    Parsons CG, Danysz W, Bartmann A, Spielmanns P, Frankiewicz T, Hesselink M, Eilbacher B, Quack G.
    Neuropharmacology; 1999 Jan; 38(1):85-108. PubMed ID: 10193901
    [Abstract] [Full Text] [Related]

  • 2. A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization.
    Gilling K, Jatzke C, Wollenburg C, Vanejevs M, Kauss V, Jirgensons A, Parsons CG.
    J Neural Transm (Vienna); 2007 Jan; 114(12):1529-37. PubMed ID: 17728997
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo.
    Parsons CG, Quack G, Bresink I, Baran L, Przegalinski E, Kostowski W, Krzascik P, Hartmann S, Danysz W.
    Neuropharmacology; 1995 Oct; 34(10):1239-58. PubMed ID: 8570022
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  • 4. Memantine and the amino-alkyl-cyclohexane MRZ 2/579 are moderate affinity uncompetitive NMDA receptor antagonists--in vitro characterisation.
    Parsons CG, Danysz W, Quack G.
    Amino Acids; 2000 Oct; 19(1):157-66. PubMed ID: 11026484
    [Abstract] [Full Text] [Related]

  • 5. Brain distribution of an uncompetitive NMDA receptor antagonist; comparison to its in vitro potency in electrophysiological studies.
    Hesselink MB, Parsons CG, Wollenburg C, Danysz W.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Aug; 360(2):144-50. PubMed ID: 10494883
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  • 6. Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices.
    Frankiewicz T, Pilc A, Parsons CG.
    Neuropharmacology; 2000 Feb 14; 39(4):631-42. PubMed ID: 10728884
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  • 8. Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices.
    Frankiewicz T, Potier B, Bashir ZI, Collingridge GL, Parsons CG.
    Br J Pharmacol; 1996 Feb 14; 117(4):689-97. PubMed ID: 8646415
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  • 10. Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors.
    Gilling KE, Jatzke C, Hechenberger M, Parsons CG.
    Neuropharmacology; 2009 Apr 14; 56(5):866-75. PubMed ID: 19371579
    [Abstract] [Full Text] [Related]

  • 11. Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.
    Parsons CG, Panchenko VA, Pinchenko VO, Tsyndrenko AY, Krishtal OA.
    Eur J Neurosci; 1996 Mar 14; 8(3):446-54. PubMed ID: 8963435
    [Abstract] [Full Text] [Related]

  • 12. Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists.
    Danysz W, Parsons CG, Jirgensons A, Kauss V, Tillner J.
    Curr Pharm Des; 2002 Mar 14; 8(10):835-43. PubMed ID: 11945134
    [Abstract] [Full Text] [Related]

  • 13. NMDA receptor antagonists to characterize rat renal organic cation transporter function.
    Fourie J, Escobar MR, Sitar DS.
    Eur J Pharmacol; 2002 Sep 27; 452(1):1-10. PubMed ID: 12323380
    [Abstract] [Full Text] [Related]

  • 14. Agonist concentration dependency of blocking kinetics but not equilibrium block of N-methyl-D-aspartate receptors by memantine.
    Gilling KE, Jatzke C, Parsons CG.
    Neuropharmacology; 2007 Sep 27; 53(3):415-20. PubMed ID: 17632186
    [Abstract] [Full Text] [Related]

  • 15. In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites.
    Woodward RM, Huettner JE, Guastella J, Keana JF, Weber E.
    Mol Pharmacol; 1995 Mar 27; 47(3):568-81. PubMed ID: 7700254
    [Abstract] [Full Text] [Related]

  • 16. Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist: patch clamp studies in cultured striatal, hippocampal, cortical and superior colliculus neurones.
    Parsons CG, Hartmann S, Spielmanns P.
    Neuropharmacology; 1998 Jun 27; 37(6):719-27. PubMed ID: 9707285
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  • 18. Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin.
    Luo J, Li W, Zhao Y, Fu H, Ma DL, Tang J, Li C, Peoples RW, Li F, Wang Q, Huang P, Xia J, Pang Y, Han Y.
    J Biol Chem; 2010 Jun 25; 285(26):19947-58. PubMed ID: 20404346
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