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Journal Abstract Search

774 related items for PubMed ID: 10197960

  • 1. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Song Y, Connor DT, Sercel AD, Sorenson RJ, Doubleday R, Unangst PC, Roth BD, Beylin VG, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.
    J Med Chem; 1999 Apr 08; 42(7):1161-9. PubMed ID: 10197960
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  • 2. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.
    J Med Chem; 1999 Apr 08; 42(7):1151-60. PubMed ID: 10197959
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  • 3. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    Riendeau D, Percival MD, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Falgueyret JP, Ford-Hutchinson AW, Gordon R, Greig G, Gresser M, Guay J, Kargman S, Léger S, Mancini JA, O'Neill G, Ouellet M, Rodger IW, Thérien M, Wang Z, Webb JK, Wong E, Chan CC.
    Br J Pharmacol; 1997 May 08; 121(1):105-17. PubMed ID: 9146894
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  • 4. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.
    Kalgutkar AS, Kozak KR, Crews BC, Hochgesang GP, Marnett LJ.
    J Med Chem; 1998 Nov 19; 41(24):4800-18. PubMed ID: 9822550
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  • 5. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
    Chan CC, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Ford-Hutchinson AW, Forrest MJ, Gauthier JY, Gordon R, Gresser M, Guay J, Kargman S, Kennedy B, Leblanc Y, Leger S, Mancini J, O'Neill GP, Ouellet M, Patrick D, Percival MD, Perrier H, Prasit P, Rodger I.
    J Pharmacol Exp Ther; 1999 Aug 19; 290(2):551-60. PubMed ID: 10411562
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  • 6. 1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.
    Khanna IK, Weier RM, Yu Y, Collins PW, Miyashiro JM, Koboldt CM, Veenhuizen AW, Currie JL, Seibert K, Isakson PC.
    J Med Chem; 1997 May 23; 40(11):1619-33. PubMed ID: 9171872
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  • 10. New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position.
    Janusz JM, Young PA, Ridgeway JM, Scherz MW, Enzweiler K, Wu LI, Gan L, Chen J, Kellstein DE, Green SA, Tulich JL, Rosario-Jansen T, Magrisso IJ, Wehmeyer KR, Kuhlenbeck DL, Eichhold TH, Dobson RL.
    J Med Chem; 1998 Aug 27; 41(18):3515-29. PubMed ID: 9719605
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  • 11. Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors.
    Gierse J, Nickols M, Leahy K, Warner J, Zhang Y, Cortes-Burgos L, Carter J, Seibert K, Masferrer J.
    Eur J Pharmacol; 2008 Jun 24; 588(1):93-8. PubMed ID: 18457826
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  • 14. 2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors.
    Black WC, Brideau C, Chan CC, Charleson S, Chauret N, Claveau D, Ethier D, Gordon R, Greig G, Guay J, Hughes G, Jolicoeur P, Leblanc Y, Nicoll-Griffith D, Ouimet N, Riendeau D, Visco D, Wang Z, Xu L, Prasit P.
    J Med Chem; 1999 Apr 08; 42(7):1274-81. PubMed ID: 10197970
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  • 15. Discovery of a novel COX-2 inhibitor as an orally potent anti-pyretic and anti-inflammatory drug: design, synthesis, and structure-activity relationship.
    Hayashi S, Sumi Y, Ueno N, Murase A, Takada J.
    Biochem Pharmacol; 2011 Oct 01; 82(7):755-68. PubMed ID: 21741371
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  • 17. Amide derivatives of [5-chloro-6-(2-chloro/fluorobenzoyl)-2-benzoxazolinone-3-yl]acetic acids as potential analgesic and anti-inflammatory compounds.
    Banoglu E, Okçelik B, Kupeli E, Unlü S, Yeşilada E, Amat M, Caturla JF, Sahin MF.
    Arch Pharm (Weinheim); 2003 Jul 01; 336(4-5):251-7. PubMed ID: 12916060
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  • 20. Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.
    Li JJ, Norton MB, Reinhard EJ, Anderson GD, Gregory SA, Isakson PC, Koboldt CM, Masferrer JL, Perkins WE, Seibert K, Zhang Y, Zweifel BS, Reitz DB.
    J Med Chem; 1996 Apr 26; 39(9):1846-56. PubMed ID: 8627608
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