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Journal Abstract Search

109 related items for PubMed ID: 10210267

  • 1. Transport kinetics of leucine enkephalin across Caco-2 monolayers: quantitative analysis for contribution of enzymatic and transport barrier.
    Quan YS, Fujita T, Tohara D, Tsuji M, Kohyama M, Yamamoto A.
    Life Sci; 1999; 64(14):1243-52. PubMed ID: 10210267
    [Abstract] [Full Text] [Related]

  • 2. Effects of various protease inhibitors on the stability and permeability of [D-Ala2,D-Leu5]enkephalin in the rat intestine: comparison with leucine enkephalin.
    Uchiyama T, Kotani A, Kishida T, Tatsumi H, Okamoto A, Fujita T, Murakami M, Muranishi S, Yamamoto A.
    J Pharm Sci; 1998 Apr; 87(4):448-52. PubMed ID: 9548897
    [Abstract] [Full Text] [Related]

  • 3.
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  • 4. Gastrointestinal absorption of peptide drug: quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine.
    Taki Y, Sakane T, Nadai T, Sezaki H, Amidon GL, Langguth P, Yamashita S.
    J Pharmacol Exp Ther; 1995 Jul; 274(1):373-7. PubMed ID: 7616421
    [Abstract] [Full Text] [Related]

  • 5. Transport and metabolism of delta sleep-inducing peptide in cultured human intestinal epithelial cell monolayers.
    Augustijns PF, Borchardt RT.
    Drug Metab Dispos; 1995 Dec; 23(12):1372-8. PubMed ID: 8689946
    [Abstract] [Full Text] [Related]

  • 6. Oral absorption of peptides: influence of pH and inhibitors on the intestinal hydrolysis of leu-enkephalin and analogues.
    Friedman DI, Amidon GL.
    Pharm Res; 1991 Jan; 8(1):93-6. PubMed ID: 2014216
    [Abstract] [Full Text] [Related]

  • 7. Transmucosal delivery of leucine enkephalin: stabilization in rabbit enzyme extracts and enhancement of permeation through mucosae.
    Sayani AP, Chun IK, Chien YW.
    J Pharm Sci; 1993 Nov; 82(11):1179-85. PubMed ID: 8289138
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of enkephalin degrading enzymes by metal chelating reagents.
    Altstein M, Blumberg S, Vogel Z.
    Adv Biochem Psychopharmacol; 1982 Nov; 33():261-70. PubMed ID: 6751033
    [Abstract] [Full Text] [Related]

  • 9. Inactivation of enkephalin by brain enzymes.
    Vogel Z, Altstein M.
    Prog Biochem Pharmacol; 1980 Nov; 16():49-59. PubMed ID: 7003599
    [Abstract] [Full Text] [Related]

  • 10. Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues.
    Wong AK, Ross BP, Chan YN, Artursson P, Lazorova L, Jones A, Toth I.
    Eur J Pharm Sci; 2002 Aug; 16(3):113-8. PubMed ID: 12128164
    [Abstract] [Full Text] [Related]

  • 11. Lipophilic derivatives of leu-enkephalinamide: in vitro permeability, stability and in vivo nasal delivery.
    Cros CD, Toth I, Blanchfield JT.
    Bioorg Med Chem; 2011 Feb 15; 19(4):1528-34. PubMed ID: 21273080
    [Abstract] [Full Text] [Related]

  • 12. Improvement of intestinal absorption of leucine enkephalin by sugar coupling and peptidase inhibitors.
    Mizuma T, Ohta K, Koyanagi A, Awazu S.
    J Pharm Sci; 1996 Aug 15; 85(8):854-7. PubMed ID: 8863276
    [Abstract] [Full Text] [Related]

  • 13. Identification and characterization of aminopeptidases from Aplysia californica.
    Bawab W, Querido E, Crine P, DesGroseillers L.
    Biochem J; 1992 Sep 15; 286 ( Pt 3)(Pt 3):967-75. PubMed ID: 1417757
    [Abstract] [Full Text] [Related]

  • 14. Optimizing oral absorption of peptides using prodrug strategies.
    Borchardt RT.
    J Control Release; 1999 Nov 01; 62(1-2):231-8. PubMed ID: 10518655
    [Abstract] [Full Text] [Related]

  • 15. Recovery of rat nasal mucosa from the effects of aminopeptidase inhibitors.
    Hussain MA, Koval CA, Shenvi AB, Aungst BJ.
    J Pharm Sci; 1990 May 01; 79(5):398-400. PubMed ID: 2352157
    [Abstract] [Full Text] [Related]

  • 16. Nasal absorption of leucine enkephalin in rats and the effects of aminopeptidase inhibition, as determined from the percentage of the dose unabsorbed.
    Hussain MA, Aungst BJ.
    Pharm Res; 1992 Oct 01; 9(10):1362-4. PubMed ID: 1448440
    [No Abstract] [Full Text] [Related]

  • 17. Specific aminopeptidases of excised human nasal epithelium and primary culture: a comparison of functional characteristics and gene transcripts expression.
    Agu RU, Obimah DU, Lyzenga WJ, Jorissen M, Massoud E, Verbeke N.
    J Pharm Pharmacol; 2009 May 01; 61(5):599-606. PubMed ID: 19405998
    [Abstract] [Full Text] [Related]

  • 18. Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the caco-2 cell monolayer system.
    Wu S, Campbell C, Koda Y, Blanchfield JT, Toth I.
    Med Chem; 2006 Mar 01; 2(2):203-11. PubMed ID: 16787368
    [Abstract] [Full Text] [Related]

  • 19. Enhancement of systemic delivery of met-enkephalin and leu-enkephalin eyedrops with permeation enhancers.
    Chiou GC, Shen ZF, Zheng YQ, Li BH.
    Methods Find Exp Clin Pharmacol; 1992 Jun 01; 14(5):361-6. PubMed ID: 1513191
    [Abstract] [Full Text] [Related]

  • 20. Reversible lipidization for the oral delivery of leu-enkephalin.
    Wang J, Hogenkamp DJ, Tran M, Li WY, Yoshimura RF, Johnstone TB, Shen WC, Gee KW.
    J Drug Target; 2006 Apr 01; 14(3):127-36. PubMed ID: 16753826
    [Abstract] [Full Text] [Related]

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