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252 related items for PubMed ID: 10214872

  • 1. DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
    Hall PD, Willingham MC, Kreitman RJ, Frankel AE.
    Leukemia; 1999 Apr; 13(4):629-33. PubMed ID: 10214872
    [Abstract] [Full Text] [Related]

  • 2. Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
    Hall PD, Kreitman RJ, Willingham MC, Frankel AE.
    Toxicol Appl Pharmacol; 1998 May; 150(1):91-7. PubMed ID: 9630457
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  • 3. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
    Feuring-Buske M, Frankel A, Gerhard B, Hogge D.
    Exp Hematol; 2000 Dec; 28(12):1390-400. PubMed ID: 11146161
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  • 4. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
    Frankel AE, Lilly M, Kreitman R, Hogge D, Beran M, Freedman MH, Emanuel PD, McLain C, Hall P, Tagge E, Berger M, Eaves C.
    Blood; 1998 Dec 01; 92(11):4279-86. PubMed ID: 9834234
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  • 7. Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF.
    Frankel AE, Hall PD, McLain C, Safa AR, Tagge EP, Kreitman RJ.
    Bioconjug Chem; 1998 Dec 01; 9(4):490-6. PubMed ID: 9667951
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  • 10. Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
    Frankel AE, Hall PD, Burbage C, Vesely J, Willingham M, Bhalla K, Kreitman RJ.
    Blood; 1997 Nov 01; 90(9):3654-61. PubMed ID: 9345050
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  • 11. Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
    Kreitman RJ, Pastan I.
    Blood; 1997 Jul 01; 90(1):252-9. PubMed ID: 9207460
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  • 12. Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins.
    Jedema I, Barge RM, Frankel AE, Willemze R, Falkenburg JH.
    Exp Hematol; 2004 Feb 01; 32(2):188-94. PubMed ID: 15102480
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  • 13. Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
    Senchenkov A, Han TY, Wang H, Frankel AE, Kottke TJ, Kaufmann SH, Cabot MC.
    Blood; 2001 Sep 15; 98(6):1927-34. PubMed ID: 11535531
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  • 17. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
    Bendel AE, Shao Y, Davies SM, Warman B, Yang CH, Waddick KG, Uckun FM, Perentesis JP.
    Leuk Lymphoma; 1997 Apr 15; 25(3-4):257-70. PubMed ID: 9168436
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  • 18. Enhanced chemosensitivity of clonogenic blasts from patients with acute myeloid leukemia by G-CSF, IL-3 or GM-CSF stimulation.
    te Boekhorst PA, Löwenberg B, Vlastuin M, Sonneveld P.
    Leukemia; 1993 Aug 15; 7(8):1191-8. PubMed ID: 7688839
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  • 19. A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells.
    Chan CH, Blazar BR, Eide CR, Kreitman RJ, Vallera DA.
    Blood; 1995 Oct 01; 86(7):2732-40. PubMed ID: 7670112
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