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Journal Abstract Search

432 related items for PubMed ID: 10215699

  • 21. Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.
    Stark H, Purand K, Ligneau X, Rouleau A, Arrang JM, Garbarg M, Schwartz JC, Schunack W.
    J Med Chem; 1996 Mar 01; 39(5):1157-63. PubMed ID: 8676353
    [Abstract] [Full Text] [Related]

  • 22. Search for novel leads for histamine H3-receptor antagonists: amine derivatives.
    Stark H, Ligneau X, Lipp R, Arrang JM, Schwartz JC, Schunack W.
    Pharmazie; 1997 Jun 01; 52(6):419-23. PubMed ID: 9260265
    [Abstract] [Full Text] [Related]

  • 23. Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist.
    Ligneau X, Lin J, Vanni-Mercier G, Jouvet M, Muir JL, Ganellin CR, Stark H, Elz S, Schunack W, Schwartz J.
    J Pharmacol Exp Ther; 1998 Nov 01; 287(2):658-66. PubMed ID: 9808693
    [Abstract] [Full Text] [Related]

  • 24. Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687).
    McLeod RL, Rizzo CA, West RE, Aslanian R, McCormick K, Bryant M, Hsieh Y, Korfmacher W, Mingo GG, Varty L, Williams SM, Shih NY, Egan RW, Hey JA.
    J Pharmacol Exp Ther; 2003 Jun 01; 305(3):1037-44. PubMed ID: 12649305
    [Abstract] [Full Text] [Related]

  • 25. Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity.
    Morini G, Comini M, Rivara M, Rivara S, Bordi F, Plazzi PV, Flammini L, Saccani F, Bertoni S, Ballabeni V, Barocelli E, Mor M.
    Bioorg Med Chem; 2008 Dec 01; 16(23):9911-24. PubMed ID: 18976927
    [Abstract] [Full Text] [Related]

  • 26. H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles.
    Mor M, Bordi F, Silva C, Rivara S, Crivori P, Plazzi PV, Ballabeni V, Caretta A, Barocelli E, Impicciatore M, Carrupt PA, Testa B.
    J Med Chem; 1997 Aug 01; 40(16):2571-8. PubMed ID: 9258364
    [Abstract] [Full Text] [Related]

  • 27. S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist.
    Garbarg M, Arrang JM, Rouleau A, Ligneau X, Tuong MD, Schwartz JC, Ganellin CR.
    J Pharmacol Exp Ther; 1992 Oct 01; 263(1):304-10. PubMed ID: 1383495
    [Abstract] [Full Text] [Related]

  • 28. Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.
    Berlin M, Ting PC, Vaccaro WD, Aslanian R, McCormick KD, Lee JF, Albanese MM, Mutahi MW, Piwinski JJ, Shih NY, Duguma L, Solomon DM, Zhou W, Sher R, Favreau L, Bryant M, Korfmacher WA, Nardo C, West RE, Anthes JC, Williams SM, Wu RL, Susan She H, Rivelli MA, Corboz MR, Hey JA.
    Bioorg Med Chem Lett; 2006 Feb 15; 16(4):989-94. PubMed ID: 16297617
    [Abstract] [Full Text] [Related]

  • 29. Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
    Kitbunnadaj R, Zuiderveld OP, De Esch IJ, Vollinga RC, Bakker R, Lutz M, Spek AL, Cavoy E, Deltent MF, Menge WM, Timmerman H, Leurs R.
    J Med Chem; 2003 Dec 04; 46(25):5445-57. PubMed ID: 14640553
    [Abstract] [Full Text] [Related]

  • 30. Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
    Pelloux-Léon N, Fkyerat A, Piripitsi A, Tertiuk W, Schunack W, Stark H, Garbarg M, Ligneau X, Arrang JM, Schwartz JC, Ganellin CR.
    J Med Chem; 2004 Jun 03; 47(12):3264-74. PubMed ID: 15163206
    [Abstract] [Full Text] [Related]

  • 31. Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
    Vaccaro WD, Sher R, Berlin M, Shih NY, Aslanian R, Schwerdt JH, McCormick KD, Piwinski JJ, West RE, Anthes JC, Williams SM, Wu RL, She HS, Rivelli MA, Mutter JC, Corboz MR, Hey JA, Favreau L.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):395-9. PubMed ID: 16246552
    [Abstract] [Full Text] [Related]

  • 32. Studies on the pharmacology of the novel histamine H3 receptor agonist Sch 50971.
    Hey JA, Aslanian R, Bolser DC, Chapman RW, Egan RW, Rizzo CA, Shih NY, Fernandez X, McLeod RL, West R, Kreutner W.
    Arzneimittelforschung; 1998 Sep 15; 48(9):881-8. PubMed ID: 9793613
    [Abstract] [Full Text] [Related]

  • 33. Evidence for tolerance following repeated dosing in rats with ciproxifan, but not with A-304121.
    Pan JB, Yao BB, Miller TR, Kroeger PE, Bennani YL, Komater VA, Esbenshade TA, Hancock AA, Decker MW, Fox GB.
    Life Sci; 2006 Aug 29; 79(14):1366-79. PubMed ID: 16730751
    [Abstract] [Full Text] [Related]

  • 34. Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.
    Esbenshade TA, Krueger KM, Miller TR, Kang CH, Denny LI, Witte DG, Yao BB, Fox GB, Faghih R, Bennani YL, Williams M, Hancock AA.
    J Pharmacol Exp Ther; 2003 Jun 29; 305(3):887-96. PubMed ID: 12606603
    [Abstract] [Full Text] [Related]

  • 35. Piperidine variations in search for non-imidazole histamine H(3) receptor ligands.
    Łazewska D, Kuder K, Ligneau X, Schwartz JC, Schunack W, Stark H, Kieć-Kononowicz K.
    Bioorg Med Chem; 2008 Sep 15; 16(18):8729-36. PubMed ID: 18774720
    [Abstract] [Full Text] [Related]

  • 36. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties.
    Esbenshade TA, Fox GB, Krueger KM, Miller TR, Kang CH, Denny LI, Witte DG, Yao BB, Pan L, Wetter J, Marsh K, Bennani YL, Cowart MD, Sullivan JP, Hancock AA.
    J Pharmacol Exp Ther; 2005 Apr 15; 313(1):165-75. PubMed ID: 15608078
    [Abstract] [Full Text] [Related]

  • 37. Replacement of imidazole by a piperidine moiety differentially affects the potency of histamine H3-receptor antagonists.
    Liedtke S, Flau K, Kathmann M, Schlicker E, Stark H, Meier G, Schunack W.
    Naunyn Schmiedebergs Arch Pharmacol; 2003 Jan 15; 367(1):43-50. PubMed ID: 12616340
    [Abstract] [Full Text] [Related]

  • 38. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
    Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH.
    J Med Chem; 2005 Feb 10; 48(3):839-48. PubMed ID: 15689168
    [Abstract] [Full Text] [Related]

  • 39. Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
    Kottke T, Sander K, Weizel L, Schneider EH, Seifert R, Stark H.
    Eur J Pharmacol; 2011 Mar 11; 654(3):200-8. PubMed ID: 21237145
    [Abstract] [Full Text] [Related]

  • 40. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats.
    Medhurst AD, Briggs MA, Bruton G, Calver AR, Chessell I, Crook B, Davis JB, Davis RP, Foley AG, Heslop T, Hirst WD, Medhurst SJ, Ociepka S, Ray A, Regan CM, Sargent B, Schogger J, Stean TO, Trail BK, Upton N, White T, Orlek B, Wilson DM.
    Biochem Pharmacol; 2007 Apr 15; 73(8):1182-94. PubMed ID: 17276409
    [Abstract] [Full Text] [Related]

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