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253 related items for PubMed ID: 10223294

  • 1. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
    Knobe KE, Berntsdotter A, Shen L, Morser J, Dahlbäck B, Villoutreix BO.
    Proteins; 1999 May 01; 35(2):218-34. PubMed ID: 10223294
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  • 3. Calcium-dependent activation of protein C by thrombin/thrombomudulin: role of negatively charged amino acids within the activation peptide of protein C.
    Friedrich U, Pötzsch B, Preissner KT, Müller-Berghaus G, Ehrlich H.
    Thromb Haemost; 1994 Oct 01; 72(4):567-72. PubMed ID: 7878634
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  • 4. Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin.
    Rezaie AR, Yang L.
    Proc Natl Acad Sci U S A; 2003 Oct 14; 100(21):12051-6. PubMed ID: 14523228
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  • 5. Amino acids 225-235** of the protein C serine-protease domain are important for the interaction with the thrombin-thrombomodulin complex.
    Vincenot A, Gaussem P, Pittet JL, Debost S, Aiach M.
    FEBS Lett; 1995 Jun 26; 367(2):153-7. PubMed ID: 7540990
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  • 7. Thrombomodulin-mediated catabolism of protein C by pleural mesothelial and vascular endothelial cells.
    Iakhiaev AV, Rezaie AR, Idell S.
    Thromb Haemost; 2007 Sep 26; 98(3):627-34. PubMed ID: 17849052
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  • 8. Mutagenesis studies toward understanding the mechanism of the cofactor function of thrombomodulin.
    Rezaie AR, Yang L.
    Biophys Chem; 2005 Oct 03; 117(3):255-61. PubMed ID: 15970373
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  • 9. Calcium-binding sites of the thrombin-thrombomodulin-protein C complex: possible implications for the effect of platelet factor 4 on the activation of vitamin K-dependent coagulation factors.
    Yang L, Rezaie AR.
    Thromb Haemost; 2007 Jun 03; 97(6):899-906. PubMed ID: 17549291
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  • 10. The Gla26 residue of protein C is required for the binding of protein C to thrombomodulin and endothelial cell protein C receptor, but not to protein S and factor Va.
    Nishioka J, Ido M, Hayashi T, Suzuki K.
    Thromb Haemost; 1996 Feb 03; 75(2):275-82. PubMed ID: 8815576
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  • 13. The functions of the first epidermal growth factor homology region of human protein C as revealed by a charge-to-alanine scanning mutagenesis investigation.
    Cheng CH, Geng JP, Castellino FJ.
    Biol Chem; 1997 Dec 03; 378(12):1491-500. PubMed ID: 9461348
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  • 14. The fourth epidermal growth factor-like domain of thrombomodulin interacts with the basic exosite of protein C.
    Yang L, Rezaie AR.
    J Biol Chem; 2003 Mar 21; 278(12):10484-90. PubMed ID: 12529320
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  • 15. The affinity of protein C for the thrombin.thrombomodulin complex is determined in a primary way by active site-dependent interactions.
    Lu G, Chhum S, Krishnaswamy S.
    J Biol Chem; 2005 Apr 15; 280(15):15471-8. PubMed ID: 15705565
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  • 16. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex.
    Rezaie AR, Esmon CT.
    Biochemistry; 1995 Sep 26; 34(38):12221-6. PubMed ID: 7547963
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  • 17. Thrombomodulin tightens the thrombin active site loops to promote protein C activation.
    Koeppe JR, Seitova A, Mather T, Komives EA.
    Biochemistry; 2005 Nov 15; 44(45):14784-91. PubMed ID: 16274226
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  • 20. Characterization of a thrombomodulin binding site on protein C and its comparison to an activated protein C binding site for factor Va.
    Gale AJ, Griffin JH.
    Proteins; 2004 Feb 15; 54(3):433-41. PubMed ID: 14747992
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