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192 related items for PubMed ID: 10224114

  • 1. Thrombopoietin signal transduction requires functional JAK2, not TYK2.
    Drachman JG, Millett KM, Kaushansky K.
    J Biol Chem; 1999 May 07; 274(19):13480-4. PubMed ID: 10224114
    [Abstract] [Full Text] [Related]

  • 2. The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
    Sattler M, Durstin MA, Frank DA, Okuda K, Kaushansky K, Salgia R, Griffin JD.
    Exp Hematol; 1995 Aug 07; 23(9):1040-8. PubMed ID: 7543416
    [Abstract] [Full Text] [Related]

  • 3. Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, JAK2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro.
    Ezumi Y, Takayama H, Okuma M.
    FEBS Lett; 1995 Oct 23; 374(1):48-52. PubMed ID: 7589510
    [Abstract] [Full Text] [Related]

  • 4. Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.
    Tortolani PJ, Johnston JA, Bacon CM, McVicar DW, Shimosaka A, Linnekin D, Longo DL, O'Shea JJ.
    Blood; 1995 Jun 15; 85(12):3444-51. PubMed ID: 7780132
    [Abstract] [Full Text] [Related]

  • 5. Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3.
    Bacon CM, Tortolani PJ, Shimosaka A, Rees RC, Longo DL, O'Shea JJ.
    FEBS Lett; 1995 Aug 14; 370(1-2):63-8. PubMed ID: 7544303
    [Abstract] [Full Text] [Related]

  • 6. The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.
    Drachman JG, Griffin JD, Kaushansky K.
    J Biol Chem; 1995 Mar 10; 270(10):4979-82. PubMed ID: 7534285
    [Abstract] [Full Text] [Related]

  • 7. Thrombopoietin signal transduction in purified murine megakaryocytes.
    Drachman JG, Sabath DF, Fox NE, Kaushansky K.
    Blood; 1997 Jan 15; 89(2):483-92. PubMed ID: 9002950
    [Abstract] [Full Text] [Related]

  • 8. The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway.
    Dorsch M, Fan PD, Danial NN, Rothman PB, Goff SP.
    J Exp Med; 1997 Dec 15; 186(12):1947-55. PubMed ID: 9396763
    [Abstract] [Full Text] [Related]

  • 9. Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.
    Drachman JG, Miyakawa Y, Luthi JN, Dahlen DD, Raney A, Geddis AE, Kaushansky K.
    J Biol Chem; 2002 Jun 28; 277(26):23544-53. PubMed ID: 11980901
    [Abstract] [Full Text] [Related]

  • 10. Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets.
    Miyakawa Y, Oda A, Druker BJ, Miyazaki H, Handa M, Ohashi H, Ikeda Y.
    Blood; 1996 Jan 15; 87(2):439-46. PubMed ID: 8555464
    [Abstract] [Full Text] [Related]

  • 11. Thrombopoietin signal transduction: studies from cell lines and primary cells.
    Drachman JG, Rojnuckarin P, Kaushansky K.
    Methods; 1999 Mar 15; 17(3):238-49. PubMed ID: 10080909
    [Abstract] [Full Text] [Related]

  • 12. Stem cell factor synergistically enhances thrombopoietin-induced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase.
    Drayer AL, Boer AK, Los EL, Esselink MT, Vellenga E.
    Stem Cells; 2005 Feb 15; 23(2):240-51. PubMed ID: 15671147
    [Abstract] [Full Text] [Related]

  • 13. Differential signalling of NH2-terminal flag-labelled thrombopoietin receptor activated by TPO or anti-FLAG antibodies.
    Millot GA, Vainchenker W, Duménil D, Svinarchuk F.
    Cell Signal; 2004 Mar 15; 16(3):355-63. PubMed ID: 14687665
    [Abstract] [Full Text] [Related]

  • 14. A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts.
    Challier C, Cocault L, Flon M, Pauchard M, Porteu F, Gisselbrecht S, Souyri M.
    Oncogene; 2000 Apr 13; 19(16):2033-42. PubMed ID: 10803464
    [Abstract] [Full Text] [Related]

  • 15. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor.
    Shimoda K, Feng J, Murakami H, Nagata S, Watling D, Rogers NC, Stark GR, Kerr IM, Ihle JN.
    Blood; 1997 Jul 15; 90(2):597-604. PubMed ID: 9226159
    [Abstract] [Full Text] [Related]

  • 16. Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
    Pallard C, Gouilleux F, Bénit L, Cocault L, Souyri M, Levy D, Groner B, Gisselbrecht S, Dusanter-Fourt I.
    EMBO J; 1995 Jun 15; 14(12):2847-56. PubMed ID: 7796811
    [Abstract] [Full Text] [Related]

  • 17. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W, Lodish HF.
    J Exp Med; 2004 Sep 06; 200(5):569-80. PubMed ID: 15337790
    [Abstract] [Full Text] [Related]

  • 18. Thrombopoietin induces tyrosine phosphorylation of a common beta subunit of GM-CSF receptor and its association with Stat5 in TF-1/TPO cells.
    Ooi J, Tojo A, Asano S, Sato Y, Oka Y.
    Biochem Biophys Res Commun; 1998 May 08; 246(1):132-6. PubMed ID: 9600081
    [Abstract] [Full Text] [Related]

  • 19. Signal transduction by the peptide which mimics the activity of thrombopoietin.
    Kimura T, Kaburaki H, Tsujino T, Watanabe Y, Kato H.
    Biochem Mol Biol Int; 1998 May 08; 44(6):1203-9. PubMed ID: 9623775
    [Abstract] [Full Text] [Related]

  • 20. Signal transduction by the receptors for thrombopoietin (c-mpL) and interleukin-3 in hematopoietic and nonhematopoietic cells.
    Morella KK, Bruno E, Kumaki S, Lai CF, Fu J, Wang HM, Murray L, Hoffman R, Timour M, Bénit L.
    Blood; 1995 Jul 15; 86(2):557-71. PubMed ID: 7605989
    [Abstract] [Full Text] [Related]

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