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466 related items for PubMed ID: 10325236

  • 1. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.
    Zhang S, Zhou Z, Gong Q, Makielski JC, January CT.
    Circ Res; 1999 May 14; 84(9):989-98. PubMed ID: 10325236
    [Abstract] [Full Text] [Related]

  • 2. Molecular determinants of dofetilide block of HERG K+ channels.
    Ficker E, Jarolimek W, Kiehn J, Baumann A, Brown AM.
    Circ Res; 1998 Feb 23; 82(3):386-95. PubMed ID: 9486667
    [Abstract] [Full Text] [Related]

  • 3. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.
    Kiehn J, Lacerda AE, Wible B, Brown AM.
    Circulation; 1996 Nov 15; 94(10):2572-9. PubMed ID: 8921803
    [Abstract] [Full Text] [Related]

  • 4. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D, Roy ML, Dennis A, Brown AM.
    FEBS Lett; 1997 Nov 03; 417(1):28-32. PubMed ID: 9395068
    [Abstract] [Full Text] [Related]

  • 5. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
    Ficker E, Jarolimek W, Brown AM.
    Mol Pharmacol; 2001 Dec 03; 60(6):1343-8. PubMed ID: 11723241
    [Abstract] [Full Text] [Related]

  • 6. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
    Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J.
    J Pharmacol Exp Ther; 2001 May 03; 297(2):753-61. PubMed ID: 11303067
    [Abstract] [Full Text] [Related]

  • 7. High affinity open channel block by dofetilide of HERG expressed in a human cell line.
    Snyders DJ, Chaudhary A.
    Mol Pharmacol; 1996 Jun 03; 49(6):949-55. PubMed ID: 8649354
    [Abstract] [Full Text] [Related]

  • 8. [3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel?
    Finlayson K, Pennington AJ, Kelly JS.
    Eur J Pharmacol; 2001 Feb 02; 412(3):203-12. PubMed ID: 11166283
    [Abstract] [Full Text] [Related]

  • 9. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.
    Spector PS, Curran ME, Keating MT, Sanguinetti MC.
    Circ Res; 1996 Mar 02; 78(3):499-503. PubMed ID: 8593709
    [Abstract] [Full Text] [Related]

  • 10. Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels.
    Park JB, Choe H, Lee YK, Ha KC, Rhee KS, Ko JK, Joo CU, Chae SW, Kwak YG.
    J Pharmacol Exp Ther; 2002 Jul 02; 302(1):314-9. PubMed ID: 12065732
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.
    Wei Z, Thomas D, Karle CA, Kathöfer S, Schenkel J, Kreye VA, Ficker E, Wible BA, Kiehn J.
    Chin Med J (Engl); 2002 May 02; 115(5):668-76. PubMed ID: 12133532
    [Abstract] [Full Text] [Related]

  • 12. Block of HERG-carried K+ currents by the new repolarization delaying agent H 345/52.
    Amos GJ, Jacobson I, Duker G, Carlsson L.
    J Cardiovasc Electrophysiol; 2003 Jun 02; 14(6):651-8. PubMed ID: 12875428
    [Abstract] [Full Text] [Related]

  • 13. Cocaine blocks HERG, but not KvLQT1+minK, potassium channels.
    Zhang S, Rajamani S, Chen Y, Gong Q, Rong Y, Zhou Z, Ruoho A, January CT.
    Mol Pharmacol; 2001 May 02; 59(5):1069-76. PubMed ID: 11306689
    [Abstract] [Full Text] [Related]

  • 14. Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241.
    Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE.
    FEBS Lett; 1997 Sep 08; 414(2):435-8. PubMed ID: 9315735
    [Abstract] [Full Text] [Related]

  • 15. Open channel block of HERG K(+) channels by vesnarinone.
    Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC.
    Mol Pharmacol; 2001 Aug 08; 60(2):244-53. PubMed ID: 11455010
    [Abstract] [Full Text] [Related]

  • 16. Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels.
    Kiehn J, Thomas D, Karle CA, Schöls W, Kübler W.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Mar 08; 359(3):212-9. PubMed ID: 10208308
    [Abstract] [Full Text] [Related]

  • 17. The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.
    Kupershmidt S, Yang IC, Hayashi K, Wei J, Chanthaphaychith S, Petersen CI, Johns DC, George AL, Roden DM, Balser JR.
    FASEB J; 2003 Dec 08; 17(15):2263-5. PubMed ID: 14525949
    [Abstract] [Full Text] [Related]

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  • 19. Dofetilide block involves interactions with open and inactivated states of HERG channels.
    Weerapura M, Hébert TE, Nattel S.
    Pflugers Arch; 2002 Feb 08; 443(4):520-31. PubMed ID: 11907818
    [Abstract] [Full Text] [Related]

  • 20. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E, Obejero-Paz CA, Zhao S, Brown AM.
    J Biol Chem; 2002 Feb 15; 277(7):4989-98. PubMed ID: 11741928
    [Abstract] [Full Text] [Related]

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