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Journal Abstract Search


120 related items for PubMed ID: 10335271

  • 21. Novel syntheses of cis and trans isomers of combretastatin A-4.
    Gaukroger K, Hadfield JA, Hepworth LA, Lawrence NJ, McGown AT.
    J Org Chem; 2001 Nov 30; 66(24):8135-8. PubMed ID: 11722216
    [Abstract] [Full Text] [Related]

  • 22. Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate.
    Holwell SE, Cooper PA, Thompson MJ, Pettit GR, Lippert LW, Martin SW, Bibby MC.
    Anticancer Res; 2002 Nov 30; 22(6C):3933-40. PubMed ID: 12553015
    [Abstract] [Full Text] [Related]

  • 23. Combretastatin A-1 phosphate a novel tubulin-binding agent with in vivo anti vascular effects in experimental tumours.
    Holwell SE, Cooper PA, Grosios K, Lippert JW, Pettit GR, Shnyder SD, Bibby MC.
    Anticancer Res; 2002 Nov 30; 22(2A):707-11. PubMed ID: 12017147
    [Abstract] [Full Text] [Related]

  • 24. Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents.
    Wu M, Sun Q, Yang C, Chen D, Ding J, Chen Y, Lin L, Xie Y.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):869-73. PubMed ID: 17174089
    [Abstract] [Full Text] [Related]

  • 25. Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.
    Hall JJ, Sriram M, Strecker TE, Tidmore JK, Jelinek CJ, Kumar GD, Hadimani MB, Pettit GR, Chaplin DJ, Trawick ML, Pinney KG.
    Bioorg Med Chem Lett; 2008 Sep 15; 18(18):5146-9. PubMed ID: 18710804
    [Abstract] [Full Text] [Related]

  • 26. Synthesis and antitumor activity of benzils related to combretastatin A-4.
    Mousset C, Giraud A, Provot O, Hamze A, Bignon J, Liu JM, Thoret S, Dubois J, Brion JD, Alami M.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3266-71. PubMed ID: 18477509
    [Abstract] [Full Text] [Related]

  • 27. Antineoplastic agents 320: synthesis of a practical pancratistatin prodrug.
    Pettit GR, Freeman S, Simpson MJ, Thompson MA, Boyd MR, Williams MD, Pettit GR, Doubek DL.
    Anticancer Drug Des; 1995 Apr 01; 10(3):243-50. PubMed ID: 7748458
    [Abstract] [Full Text] [Related]

  • 28. Antineoplastic agents. 565. Synthesis of combretastatin D-2 phosphate and dihydro-combretastatin D-2.
    Pettit GR, Quistorf PD, Fry JA, Herald DL, Hamel E, Chapuis JC.
    J Nat Prod; 2009 May 22; 72(5):876-83. PubMed ID: 20161135
    [Abstract] [Full Text] [Related]

  • 29. Synthesis and anti-proliferative in-vitro activity of two natural dihydrostilbenes and their analogues.
    Zhang WG, Zhao R, Ren J, Ren LX, Lin JG, Liu DL, Wu YL, Yao XS.
    Arch Pharm (Weinheim); 2007 May 22; 340(5):244-50. PubMed ID: 17516577
    [Abstract] [Full Text] [Related]

  • 30. Antineoplastic agents. 511. Direct phosphorylation of phenpanstatin and pancratistatin.
    Pettit GR, Melody N, Herald DL.
    J Nat Prod; 2004 Mar 22; 67(3):322-7. PubMed ID: 15043403
    [Abstract] [Full Text] [Related]

  • 31. Medicinal chemistry of combretastatin A4: present and future directions.
    Tron GC, Pirali T, Sorba G, Pagliai F, Busacca S, Genazzani AA.
    J Med Chem; 2006 Jun 01; 49(11):3033-44. PubMed ID: 16722619
    [No Abstract] [Full Text] [Related]

  • 32. Antineoplastic agents 440. Asymmetric synthesis and evaluation of the combretastatin A-1 SAR probes (1S,2S)- and (1R,2R)-1, 2-dihydroxy- 1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3' ',4' ',5' '-trimethoxyphenyl)-ethane.
    Pettit GR, Lippert JW, Herald DL, Hamel E, Pettit RK.
    J Nat Prod; 2000 Jul 01; 63(7):969-74. PubMed ID: 10924176
    [Abstract] [Full Text] [Related]

  • 33. Design, synthesis and biological evaluation of novel stilbene-based antitumor agents.
    Simoni D, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Grisolia G, Tripathi A, Kellogg GE, Durrant D, Lee RM.
    Bioorg Med Chem; 2009 Jan 15; 17(2):512-22. PubMed ID: 19117761
    [Abstract] [Full Text] [Related]

  • 34. Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate.
    Kirwan IG, Loadman PM, Swaine DJ, Anthoney DA, Pettit GR, Lippert JW, Shnyder SD, Cooper PA, Bibby MC.
    Clin Cancer Res; 2004 Feb 15; 10(4):1446-53. PubMed ID: 14977848
    [Abstract] [Full Text] [Related]

  • 35. Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1.
    Tanpure RP, Nguyen BL, Strecker TE, Aguirre S, Sharma S, Chaplin DJ, Siim BG, Hamel E, Lippert JW, Pettit GR, Trawick ML, Pinney KG.
    J Nat Prod; 2011 Jul 22; 74(7):1568-74. PubMed ID: 21718055
    [Abstract] [Full Text] [Related]

  • 36. Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry.
    Bio M, Rajaputra P, Nkepang G, Awuah SG, Hossion AM, You Y.
    J Med Chem; 2013 May 23; 56(10):3936-42. PubMed ID: 23631389
    [Abstract] [Full Text] [Related]

  • 37. Antineoplastic agents. 548. Synthesis of iodo- and diiodocombstatin phosphate prodrugs.
    Pettit GR, Rosenberg HJ, Dixon R, Knight JC, Hamel E, Chapuis JC, Pettit RK, Hogan F, Sumner B, Ain KB, Trickey-Platt B.
    J Nat Prod; 2012 Mar 23; 75(3):385-93. PubMed ID: 22324723
    [Abstract] [Full Text] [Related]

  • 38. Novel prodrug approach for tertiary amines: synthesis and preliminary evaluation of N-phosphonooxymethyl prodrugs.
    Krise JP, Zygmunt J, Georg GI, Stella VJ.
    J Med Chem; 1999 Aug 12; 42(16):3094-100. PubMed ID: 10447953
    [Abstract] [Full Text] [Related]

  • 39. Antineoplastic agents 500. Narcistatin.
    Pettit GR, Melody N, Simpson M, Thompson M, Herald DL, Knight JC.
    J Nat Prod; 2003 Jan 12; 66(1):92-6. PubMed ID: 12542352
    [Abstract] [Full Text] [Related]

  • 40. Antineoplastic agents. 552. Oxidation of combretastatin A-1: trapping the o-quinone intermediate considered the metabolic product of the corresponding phosphate prodrug.
    Pettit GR, Thornhill AJ, Moser BR, Hogan F.
    J Nat Prod; 2008 Sep 12; 71(9):1561-3. PubMed ID: 18729517
    [Abstract] [Full Text] [Related]


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