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480 related items for PubMed ID: 10360126

  • 1. Rapid release of antipsychotic drugs from dopamine D2 receptors: an explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine.
    Seeman P, Tallerico T.
    Am J Psychiatry; 1999 Jun; 156(6):876-84. PubMed ID: 10360126
    [Abstract] [Full Text] [Related]

  • 2. Time course of central nervous dopamine-D2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel) in patients with schizophrenia.
    Gefvert O, Bergström M, Långström B, Lundberg T, Lindström L, Yates R.
    Psychopharmacology (Berl); 1998 Jan; 135(2):119-26. PubMed ID: 9497016
    [Abstract] [Full Text] [Related]

  • 3. A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy.
    Kapur S, Zipursky R, Jones C, Shammi CS, Remington G, Seeman P.
    Arch Gen Psychiatry; 2000 Jun; 57(6):553-9. PubMed ID: 10839333
    [Abstract] [Full Text] [Related]

  • 4. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors.
    Seeman P, Tallerico T.
    Mol Psychiatry; 1998 Mar; 3(2):123-34. PubMed ID: 9577836
    [Abstract] [Full Text] [Related]

  • 5. Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics.
    Tauscher J, Hussain T, Agid O, Verhoeff NP, Wilson AA, Houle S, Remington G, Zipursky RB, Kapur S.
    Am J Psychiatry; 2004 Sep; 161(9):1620-5. PubMed ID: 15337652
    [Abstract] [Full Text] [Related]

  • 6. Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia.
    Kapur S, Zipursky RB, Remington G.
    Am J Psychiatry; 1999 Feb; 156(2):286-93. PubMed ID: 9989565
    [Abstract] [Full Text] [Related]

  • 7. Occupancy of striatal and extrastriatal dopamine D2 receptors by clozapine and quetiapine.
    Kessler RM, Ansari MS, Riccardi P, Li R, Jayathilake K, Dawant B, Meltzer HY.
    Neuropsychopharmacology; 2006 Sep; 31(9):1991-2001. PubMed ID: 16738543
    [Abstract] [Full Text] [Related]

  • 8. Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancy--a simulation study based on experimental data.
    Olsson H, Farde L.
    Neuroimage; 2001 Oct; 14(4):936-45. PubMed ID: 11554812
    [Abstract] [Full Text] [Related]

  • 9. N-[11C]methylspiperone PET, in contrast to [11C]raclopride, fails to detect D2 receptor occupancy by an atypical neuroleptic.
    Hagberg G, Gefvert O, Bergström M, Wieselgren IM, Lindström L, Wiesel FA, Långström B.
    Psychiatry Res; 1998 Jun 30; 82(3):147-60. PubMed ID: 9754439
    [Abstract] [Full Text] [Related]

  • 10. Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas.
    Vernaleken I, Janouschek H, Raptis M, Hellmann S, Veselinovic T, Bröcheler A, Boy C, Cumming P, Hiemke C, Rösch F, Schäfer WM, Gründer G.
    Int J Neuropsychopharmacol; 2010 Aug 30; 13(7):951-60. PubMed ID: 20392299
    [Abstract] [Full Text] [Related]

  • 11. Atypical antipsychotics: mechanism of action.
    Seeman P.
    Can J Psychiatry; 2002 Feb 30; 47(1):27-38. PubMed ID: 11873706
    [Abstract] [Full Text] [Related]

  • 12. IBZM SPECT imaging of striatal dopamine-2 receptors in psychotic patients treated with the novel antipsychotic substance quetiapine in comparison to clozapine and haloperidol.
    Küfferle B, Tauscher J, Asenbaum S, Vesely C, Podreka I, Brücke T, Kasper S.
    Psychopharmacology (Berl); 1997 Oct 30; 133(4):323-8. PubMed ID: 9372530
    [Abstract] [Full Text] [Related]

  • 13. Striatal and extra-striatal D(2)/D(3) dopamine receptor occupancy by quetiapine in vivo. [(123)I]-epidepride single photon emission tomography(SPET) study.
    Stephenson CM, Bigliani V, Jones HM, Mulligan RS, Acton PD, Visvikis D, Ell PJ, Kerwin RW, Pilowsky LS.
    Br J Psychiatry; 2000 Nov 30; 177():408-15. PubMed ID: 11059993
    [Abstract] [Full Text] [Related]

  • 14. Error analysis for PET measurement of dopamine D2 receptor occupancy by antipsychotics with [11C]raclopride and [11C]FLB 457.
    Ikoma Y, Ito H, Arakawa R, Okumura M, Seki C, Shidahara M, Takahashi H, Kimura Y, Kanno I, Suhara T.
    Neuroimage; 2008 Oct 01; 42(4):1285-94. PubMed ID: 18585466
    [Abstract] [Full Text] [Related]

  • 15. Comparison of D₂ dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects.
    Nord M, Nyberg S, Brogren J, Jucaite A, Halldin C, Farde L.
    Int J Neuropsychopharmacol; 2011 Nov 01; 14(10):1357-66. PubMed ID: 21477416
    [Abstract] [Full Text] [Related]

  • 16. Time course of dopamine D2 receptor occupancy by clozapine with medium and high plasma concentrations.
    Takano A, Suhara T, Kusumi I, Takahashi Y, Asai Y, Yasuno F, Ichimiya T, Inoue M, Sudo Y, Koyama T.
    Prog Neuropsychopharmacol Biol Psychiatry; 2006 Jan 01; 30(1):75-81. PubMed ID: 16040180
    [Abstract] [Full Text] [Related]

  • 17. Iodine-123-iodobenzamide SPECT assessment of dopamine D2 receptor occupancy in riperidone-treated schizophrenic patients.
    Dresel S, Tatsch K, Dähne I, Mager T, Scherer J, Hahn K.
    J Nucl Med; 1998 Jul 01; 39(7):1138-42. PubMed ID: 9669383
    [Abstract] [Full Text] [Related]

  • 18. No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457.
    Talvik M, Nordström AL, Nyberg S, Olsson H, Halldin C, Farde L.
    Am J Psychiatry; 2001 Jun 01; 158(6):926-30. PubMed ID: 11384901
    [Abstract] [Full Text] [Related]

  • 19. Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors.
    Malmberg A, Jackson DM, Eriksson A, Mohell N.
    Mol Pharmacol; 1993 May 01; 43(5):749-54. PubMed ID: 8099194
    [Abstract] [Full Text] [Related]

  • 20. Quetiapine: an effective antipsychotic in first-episode schizophrenia despite only transiently high dopamine-2 receptor blockade.
    Tauscher-Wisniewski S, Kapur S, Tauscher J, Jones C, Daskalakis ZJ, Papatheodorou G, Epstein I, Christensen BK, Zipursky RB.
    J Clin Psychiatry; 2002 Nov 01; 63(11):992-7. PubMed ID: 12444812
    [Abstract] [Full Text] [Related]


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