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Journal Abstract Search

316 related items for PubMed ID: 10368274

  • 1. Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors.
    Bond CS, Zhang Y, Berriman M, Cunningham ML, Fairlamb AH, Hunter WN.
    Structure; 1999 Jan 15; 7(1):81-9. PubMed ID: 10368274
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  • 2. Identification of potential trypanothione reductase inhibitors among commercially available β-carboline derivatives using chemical space, lead-like and drug-like filters, pharmacophore models and molecular docking.
    Rodríguez-Becerra J, Cáceres-Jensen L, Hernández-Ramos J, Barrientos L.
    Mol Divers; 2017 Aug 15; 21(3):697-711. PubMed ID: 28656524
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  • 3. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase.
    Duyzend MH, Clark CT, Simmons SL, Johnson WB, Larson AM, Leconte AM, Wills AW, Ginder-Vogel M, Wilhelm AK, Czechowicz JA, Alberg DG.
    J Enzyme Inhib Med Chem; 2012 Dec 15; 27(6):784-94. PubMed ID: 22085139
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  • 4. Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.
    Stoll VS, Simpson SJ, Krauth-Siegel RL, Walsh CT, Pai EF.
    Biochemistry; 1997 May 27; 36(21):6437-47. PubMed ID: 9174360
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  • 7. Molecular docking of a series of peptidomimetics in the trypanothione binding site of T. cruzi trypanothione reductase.
    da Rocha Pita SS, Cirino JJ, de Alencastro RB, Castro HC, Rodrigues CR, Albuquerque MG.
    J Mol Graph Model; 2009 Nov 27; 28(4):330-5. PubMed ID: 19766515
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  • 8. Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.
    Aguirre G, Cabrera E, Cerecetto H, Di Maio R, González M, Seoane G, Duffaut A, Denicola A, Gil MJ, Martínez-Merino V.
    Eur J Med Chem; 2004 May 27; 39(5):421-31. PubMed ID: 15110968
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  • 10. Crystal structure of the Trypanosoma cruzi trypanothione reductase.mepacrine complex.
    Jacoby EM, Schlichting I, Lantwin CB, Kabsch W, Krauth-Siegel RL.
    Proteins; 1996 Jan 27; 24(1):73-80. PubMed ID: 8628734
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  • 14. Trypanothione reductase: a target protein for a combined in vitro and in silico screening approach.
    Beig M, Oellien F, Garoff L, Noack S, Krauth-Siegel RL, Selzer PM.
    PLoS Negl Trop Dis; 2015 Jan 27; 9(6):e0003773. PubMed ID: 26042772
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  • 16. Inhibitors of trypanothione reductase as potential antitrypanosomal drugs.
    Chan C, Yin H, Garforth J, McKie JH, Jaouhari RA, Douglas KT, Fairlamb AH, Croft SL.
    Biochem Soc Trans; 1995 Nov 27; 23(4):511S. PubMed ID: 8654696
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  • 17. Active site of trypanothione reductase. A target for rational drug design.
    Hunter WN, Bailey S, Habash J, Harrop SJ, Helliwell JR, Aboagye-Kwarteng T, Smith K, Fairlamb AH.
    J Mol Biol; 1992 Sep 05; 227(1):322-33. PubMed ID: 1522596
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  • 18. Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution.
    Bailey S, Smith K, Fairlamb AH, Hunter WN.
    Eur J Biochem; 1993 Apr 01; 213(1):67-75. PubMed ID: 8477734
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  • 19. Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
    Jockers-Scherübl MC, Schirmer RH, Krauth-Siegel RL.
    Eur J Biochem; 1989 Mar 15; 180(2):267-72. PubMed ID: 2647489
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  • 20. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
    Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH.
    J Med Chem; 1998 Jan 15; 41(2):148-56. PubMed ID: 9457238
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