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90 related items for PubMed ID: 10368676

  • 1. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.
    Taatjes DJ, Koch TH.
    Anticancer Res; 1999; 19(2A):1201-8. PubMed ID: 10368676
    [Abstract] [Full Text] [Related]

  • 2. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
    Taatjes DJ, Fenick DJ, Koch TH.
    Chem Res Toxicol; 1999 Jul; 12(7):588-96. PubMed ID: 10409398
    [Abstract] [Full Text] [Related]

  • 3. Doxorubicin-formaldehyde conjugate, doxoform: induction of apoptosis relative to doxorubicin.
    Burke PJ, Koch TH.
    Anticancer Res; 2001 Jul; 21(4A):2753-60. PubMed ID: 11724351
    [Abstract] [Full Text] [Related]

  • 4. Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells.
    Taatjes DJ, Fenick DJ, Koch TH.
    J Med Chem; 1998 Apr 09; 41(8):1306-14. PubMed ID: 9548820
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.
    Burke PJ, Koch TH.
    J Med Chem; 2004 Feb 26; 47(5):1193-206. PubMed ID: 14971899
    [Abstract] [Full Text] [Related]

  • 6. Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells.
    Taatjes DJ, Koch TH.
    Curr Med Chem; 2001 Jan 26; 8(1):15-29. PubMed ID: 11172689
    [Abstract] [Full Text] [Related]

  • 7. Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
    Fenick DJ, Taatjes DJ, Koch TH.
    J Med Chem; 1997 Aug 01; 40(16):2452-61. PubMed ID: 9258351
    [Abstract] [Full Text] [Related]

  • 8. A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system.
    Wong HL, Bendayan R, Rauth AM, Xue HY, Babakhanian K, Wu XY.
    J Pharmacol Exp Ther; 2006 Jun 01; 317(3):1372-81. PubMed ID: 16547167
    [Abstract] [Full Text] [Related]

  • 9. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.
    Goren D, Horowitz AT, Tzemach D, Tarshish M, Zalipsky S, Gabizon A.
    Clin Cancer Res; 2000 May 01; 6(5):1949-57. PubMed ID: 10815920
    [Abstract] [Full Text] [Related]

  • 10. The role of biotransformation in anthracycline-induced cardiotoxicity in mice.
    de Jong J, Schoofs PR, Snabilié AM, Bast A, van der Vijgh WJ.
    J Pharmacol Exp Ther; 1993 Sep 01; 266(3):1312-20. PubMed ID: 8371139
    [Abstract] [Full Text] [Related]

  • 11. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs.
    Kato S, Burke PJ, Fenick DJ, Taatjes DJ, Bierbaum VM, Koch TH.
    Chem Res Toxicol; 2000 Jun 01; 13(6):509-16. PubMed ID: 10858324
    [Abstract] [Full Text] [Related]

  • 12. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
    Podell ER, Harrington DJ, Taatjes DJ, Koch TH.
    Acta Crystallogr D Biol Crystallogr; 1999 Sep 01; 55(Pt 9):1516-23. PubMed ID: 10489446
    [Abstract] [Full Text] [Related]

  • 13. MRP1 not MDR1 gene expression is the predominant mechanism of acquired multidrug resistance in two prostate carcinoma cell lines.
    Zalcberg J, Hu XF, Slater A, Parisot J, El-Osta S, Kantharidis P, Chou ST, Parkin JD.
    Prostate Cancer Prostatic Dis; 2000 Aug 01; 3(2):66-75. PubMed ID: 12497102
    [Abstract] [Full Text] [Related]

  • 14. 2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer.
    Qadan LR, Perez-Stable CM, Anderson C, D'Ippolito G, Herron A, Howard GA, Roos BA.
    Biochem Biophys Res Commun; 2001 Aug 03; 285(5):1259-66. PubMed ID: 11478793
    [Abstract] [Full Text] [Related]

  • 15. Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice.
    Suy S, Mitchell JB, Samuni A, Mueller S, Kasid U.
    Cancer; 2005 Mar 15; 103(6):1302-13. PubMed ID: 15685617
    [Abstract] [Full Text] [Related]

  • 16. Induction of apoptosis in neoplastic cells by anthracycline antitumor drugs: nuclear and cytoplasmic triggering?
    Serafino A, Sinibaldi-Vallebona P, Pierimarchi P, Bernard P, Gaudiano G, Massa C, Rasi G, Ranagnan G.
    Anticancer Res; 1999 Mar 15; 19(3A):1909-18. PubMed ID: 10470135
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxic activity, accumulation, and intracellular distribution of anthracycline antibiotics and their conjugates with the epidermal growth factor in sensitive and resistant MCF-7 cells.
    Lutsenko SV, Feldman NB, Gumanov SG, Rodina AV, Severin SE.
    Biochemistry (Mosc); 2000 Nov 15; 65(11):1299-304. PubMed ID: 11112847
    [Abstract] [Full Text] [Related]

  • 18. Poly(ethylene glycol)-poly(ester-carbonate) block copolymers carrying PEG-peptidyl-doxorubicin pendant side chains: synthesis and evaluation as anticancer conjugates.
    Andersson L, Davies J, Duncan R, Ferruti P, Ford J, Kneller S, Mendichi R, Pasut G, Schiavon O, Summerford C, Tirk A, Veronese FM, Vincenzi V, Wu G.
    Biomacromolecules; 2005 Nov 15; 6(2):914-26. PubMed ID: 15762660
    [Abstract] [Full Text] [Related]

  • 19. 4'-Epidoxorubicin to re-explore anthracycline degradation in cardiomyocytes.
    Menna P, Salvatorelli E, Minotti G.
    Chem Res Toxicol; 2009 Jun 15; 22(6):978-83. PubMed ID: 19397277
    [Abstract] [Full Text] [Related]

  • 20. WP744, a novel anthracycline with enhanced proapoptotic and antileukemic activity.
    Faderl S, Estrov Z, Kantarjian HM, Harris D, Van Q, Fokt I, Przewloka T, Godlewski C, Woynarowski JM, Priebe W.
    Anticancer Res; 2001 Jun 15; 21(6A):3777-84. PubMed ID: 11911247
    [Abstract] [Full Text] [Related]

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